成人酸血症与水杨酸盐中毒
Acidaemia and salicylate poisoning in adults.
作者信息
Proudfoot A T, Brown S S
出版信息
Br Med J. 1969 May 31;2(5656):547-50. doi: 10.1136/bmj.2.5656.547.
Abstract
A review of the arterial acid-base status on admission to hospital of 62 adults with severe salicylate poisoning showed that arterial pH was normal or high in most patients, but low in 8. The mean plasma salicylate concentrations of the acidaemic and nonacidaemic patients were similar and the difference in arterial pH was associated with a marked fall in standard bicarbonate in the former group. No significant difference of Pco(2) between the two groups was found, and hence no simple relationship exists between hypocapnia and the development of acidaemia in salicylate poisoning. Acidaemia is shown to be associated with impaired consciousness and to carry a grave prognosis.
摘要
对62例重度水杨酸盐中毒成人入院时的动脉酸碱状态进行回顾性分析发现，大多数患者的动脉pH值正常或偏高，但有8例偏低。酸血症患者和非酸血症患者的平均血浆水杨酸盐浓度相似，动脉pH值的差异与前一组标准碳酸氢盐的显著下降有关。两组之间的Pco(2)无显著差异，因此在水杨酸盐中毒中，低碳酸血症与酸血症的发生之间不存在简单的关系。酸血症与意识障碍有关，预后严重。
相似文献
1
Acidaemia and salicylate poisoning in adults.成人酸血症与水杨酸盐中毒
Br Med J. 1969 May 31;2(5656):547-50. doi: 10.1136/bmj.2.5656.547.
2
Salicylate poisoning. Comparison of acetazolamide administration and alkaline diuresis in the treatment of experimental salicylate intoxication in puppies.水杨酸盐中毒。乙酰唑胺给药与碱性利尿在幼犬实验性水杨酸盐中毒治疗中的比较。
Am J Dis Child. 1973 May;125(5):668-74. doi: 10.1001/archpedi.1973.04160050022005.
3
Blood lactate and ketone body concentrations in salicylate intoxication.水杨酸盐中毒时的血乳酸和酮体浓度。
Hum Toxicol. 1986 Dec;5(6):363-6. doi: 10.1177/096032718600500604.
4
Salicylate intoxication.
N Engl J Med. 1973 May 24;288(21):1110-3. doi: 10.1056/NEJM197305242882107.
5
Negative anion gap metabolic acidosis in salicylate overdose--a zebra!水杨酸过量导致的阴离子间隙正常型代谢性酸中毒——一只斑马！
Am J Emerg Med. 2013 Oct;31(10):1536.e3-4. doi: 10.1016/j.ajem.2013.05.031. Epub 2013 Jul 16.
6
Acetazolamide and sodium bicarbonate in treatment of salicylate poisoning in adults.乙酰唑胺和碳酸氢钠治疗成人水杨酸盐中毒
Br Med J. 1969 Jan 4;1(5635):16-9. doi: 10.1136/bmj.1.5635.16.
7
Chronic salicylate poisoning and severe malaria.
Lancet. 1996 Jun 22;347(9017):1736-7. doi: 10.1016/s0140-6736(96)90809-0.
8
Salicylate poisoning.
Am Fam Physician. 1973 Nov;8(5):102-6.
9
Acute salicylate poisoning: risk factors for severe outcome.急性水杨酸盐中毒：严重后果的危险因素
Clin Toxicol (Phila). 2017 Mar;55(3):175-180. doi: 10.1080/15563650.2016.1271127. Epub 2017 Jan 9.
10
Chronic respiratory alkalosis. The effect of sustained hyperventilation on renal regulation of acid-base equilibrium.慢性呼吸性碱中毒。持续过度通气对肾脏酸碱平衡调节的影响。
N Engl J Med. 1991 May 16;324(20):1394-401. doi: 10.1056/NEJM199105163242003.
引用本文的文献
1
Common errors in the management of poisoning.中毒处理中的常见错误。
J R Coll Physicians Lond. 1980 Apr;14(2):114-6.
2
Diuresis or urinary alkalinisation for salicylate poisoning?对于水杨酸盐中毒，是采用利尿还是使尿液碱化？
Br Med J (Clin Res Ed). 1982 Nov 13;285(6352):1383-6. doi: 10.1136/bmj.285.6352.1383.
3
Acute poisoning: organization and work-load of a treatment centre.急性中毒：一个治疗中心的组织与工作量
Br Med J. 1969 Aug 30;3(5669):489-93. doi: 10.1136/bmj.3.5669.489.
4
Host resistance and survival in carcinoma of breast: a study of 104 cases of medullary carcinoma in a series of 1,411 cases of breast cancer followed for 20 years.乳腺癌患者的宿主抵抗力与生存率：对1411例乳腺癌患者中的104例髓样癌患者进行了为期20年的随访研究。
Br Med J. 1970 Jul 25;3(5716):181-8. doi: 10.1136/bmj.3.5716.181.
5
Acute salicylate poisoning.急性水杨酸盐中毒
Br Med J. 1972 Jan 29;1(5795):263-4.
6
Acute poisoning: some myths and misconceptions.急性中毒：一些误区和误解。
Br Med J. 1971 Mar 6;1(5748):519-22. doi: 10.1136/bmj.1.5748.519.
7
Non-narcotic analgesics. Problems of overdosage.非麻醉性镇痛药。过量用药问题。
Drugs. 1986;32 Suppl 4:177-205. doi: 10.2165/00003495-198600324-00013.
8
Arterial chemoreceptor involvement in salicylate-induced hyperventilation in rats.动脉化学感受器参与大鼠水杨酸盐诱导的通气过度。
Br J Pharmacol. 1989 Oct;98(2):413-24. doi: 10.1111/j.1476-5381.1989.tb12612.x.
9
A practical approach to acid-base disorders.酸碱平衡紊乱的实用处理方法。
West J Med. 1991 Aug;155(2):146-51.
10
Salicylate intoxication in the elderly. Recognition and recommendations on how to prevent it.老年人水杨酸盐中毒。识别方法及预防建议。
Drugs Aging. 1992 Jan-Feb;2(1):20-34. doi: 10.2165/00002512-199202010-00004.
本文引用的文献
1
CHRONIC SALICYLATE INTOXICATION IN ADULTS.成人慢性水杨酸盐中毒
JAMA. 1965 Aug 16;193:555-8. doi: 10.1001/jama.1965.03090070005001.
2
ACID-BASE BALANCE IN CEREBROSPINAL FLUID.脑脊液中的酸碱平衡
Arch Neurol. 1965 May;12:479-96. doi: 10.1001/archneur.1965.00460290035006.
3
ORGANIC ACID EXCRETION IN SALICYLATE INTOXICATION.水杨酸盐中毒时的有机酸排泄
J Pediatr. 1965 Mar;66:658-66. doi: 10.1016/s0022-3476(65)80129-9.
4
TREATMENT OF SEVERE ASPIRIN POISONING WITHOUT DIALYSIS.
Lancet. 1964 Jun 27;2(7348):1409-12. doi: 10.1016/s0140-6736(64)91982-8.
5
6
Salicylate intoxication with special reference to the development of hypokalemia.水杨酸盐中毒，特别提及低钾血症的发生
Am J Med. 1959 Jun;26(6):869-82. doi: 10.1016/0002-9343(59)90209-8.
7
Disturbances of acid-base equilibrium in salicylate intoxication.
Pediatrics. 1959 Feb;23(2):260-85.
8
The respiratory and circulatory actions of salicylate.水杨酸盐的呼吸和循环作用。
Am J Med. 1955 Oct;19(4):498-508. doi: 10.1016/0002-9343(55)90342-9.
9
Specific therapy for salicylism.
N Engl J Med. 1955 Aug 11;253(6):213-7. doi: 10.1056/NEJM195508112530602.
10
The acid-base disturbance in salicylate intoxication.
Medicine (Baltimore). 1954 Feb;33(1):1-13. doi: 10.1097/00005792-195402000-00001.
Zotero 插件