Walter P R, Philippe E, Nguemby-Mbina C, Chamlian A
Hum Pathol. 1984 Dec;15(12):1145-6. doi: 10.1016/s0046-8177(84)80309-3.
Three Kaposi's sarcoma biopsy specimens obtained from three African patients with typical nodular cutaneous tumors were investigated morphologically for cellular modifications suggestive of a viral origin. In one case a Kaposi's sarcoma cell of the endothelial type contained a few intranuclear herpes-type viral inclusions. The present findings complement previous reports of herpes-type viral particles in Kaposi's sarcoma cultured cell lines and suggest that, at least under certain conditions, Kaposi's sarcoma cells enter a virus-producing phase.
对从三名患有典型结节性皮肤肿瘤的非洲患者身上获取的三份卡波西肉瘤活检标本进行了形态学研究,以寻找提示病毒起源的细胞变化。在一例中,内皮型卡波西肉瘤细胞含有一些核内疱疹型病毒包涵体。本研究结果补充了先前关于卡波西肉瘤培养细胞系中疱疹型病毒颗粒的报道,并表明,至少在某些情况下,卡波西肉瘤细胞进入了病毒产生阶段。