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Immune-complex inhibition of lymphocyte Fc gamma-receptors in primary biliary cirrhosis: a possible immunomodulatory mechanism.

作者信息

Sandilands G P, Galbraith I, Reid F M, Mills P R, MacSween R N

出版信息

Lancet. 1980 Jul 5;2(8184):9-13. doi: 10.1016/s0140-6736(80)92890-1.

DOI:10.1016/s0140-6736(80)92890-1
PMID:6104265
Abstract

20 patients with primary biliary cirrhosis (PBC) had circulating IgG-containing immune complexes. These complexes bind to lymphocyte Fc gamma-receptors in vitro; there was also evidence for in-vivo binding. Such in-vivo binding to T and K lymphocytes may exert an immunomodulatory effect on these cells, and may also explain some of the serological and cellular abnormalities in PBC.

摘要

相似文献

1
Immune-complex inhibition of lymphocyte Fc gamma-receptors in primary biliary cirrhosis: a possible immunomodulatory mechanism.
Lancet. 1980 Jul 5;2(8184):9-13. doi: 10.1016/s0140-6736(80)92890-1.
2
Serum Fc gamma-receptor-like molecules in primary biliary cirrhosis: a possible immunoregulatory mechanism.原发性胆汁性肝硬化中的血清Fcγ受体样分子：一种可能的免疫调节机制。
Immunology. 1984 Oct;53(2):315-24.
3
[Human lymphocyte receptors for the Fc ends of IgG].[人类针对IgG Fc末端的淋巴细胞受体]
C R Seances Soc Biol Fil. 1980;174(4):686-701.
4
Defective Fc receptor-mediated clearance in patients with primary biliary cirrhosis.原发性胆汁性肝硬化患者中Fc受体介导的清除功能缺陷。
Gastroenterology. 1991 Oct;101(4):1076-82. doi: 10.1016/0016-5085(91)90736-5.
5
Mononuclear cell complement receptor blockade in primary biliary cirrhosis.原发性胆汁性肝硬化中的单核细胞补体受体阻断
Gut. 1985 Jan;26(1):20-5. doi: 10.1136/gut.26.1.20.
6
Immune complex-mediated inhibition of lymphocyte Fc-gamma receptors in the plasma of patients with type 1 (insulin-dependent) diabetes mellitus: association with anti-ssDNA antibodies.1型（胰岛素依赖型）糖尿病患者血浆中免疫复合物介导的淋巴细胞Fc-γ受体抑制：与抗单链DNA抗体的关联
Clin Immunol Immunopathol. 1990 Feb;54(2):228-36. doi: 10.1016/0090-1229(90)90084-4.
7
Fc receptors on rabbit lymphocytes. Existence of receptors for IgG antibody complexed with antigen; conditions for its detection.兔淋巴细胞上的Fc受体。与抗原复合的IgG抗体受体的存在；其检测条件。
Eur J Immunol. 1980 Mar;10(3):192-7. doi: 10.1002/eji.1830100307.
8
[Primary biliary cirrhosis--an immunological problem].
Sov Med. 1984(11):51-5.
9
The ER-rosette inhibition assay as a test for immune complexes.作为免疫复合物检测方法的红细胞玫瑰花结抑制试验。
J Immunol Methods. 1980;36(1):1-11. doi: 10.1016/0022-1759(80)90089-7.
10
Demonstration of immune complexes containing the ribonucleoprotein antigen Ro in primary biliary cirrhosis.原发性胆汁性肝硬化中含核糖核蛋白抗原Ro的免疫复合物的证实。
Gastroenterology. 1986 Mar;90(3):724-7. doi: 10.1016/0016-5085(86)91129-7.

引用本文的文献

1
Evaluation of serum rosette inhibitory factors in chronic liver disease.慢性肝病血清玫瑰花结抑制因子的评估
Clin Exp Immunol. 1983 Jul;53(1):145-50.
2
Alterations in T lymphocytes and T-lymphocyte subpopulations in patients with syphilis.梅毒患者T淋巴细胞及T淋巴细胞亚群的改变。
Br J Vener Dis. 1982 Feb;58(1):18-22. doi: 10.1136/sti.58.1.18.
3
Circulating immune complexes in primary biliary cirrhosis: interactions with lymphoid cells.原发性胆汁性肝硬化中的循环免疫复合物：与淋巴细胞的相互作用。
Clin Exp Immunol. 1982 Oct;50(1):7-16.
4
Clonal analysis of liver-derived T cells of patients with primary biliary cirrhosis.原发性胆汁性肝硬化患者肝脏来源T细胞的克隆分析。
Clin Exp Immunol. 1989 May;76(2):210-5.
5
Anti-mitochondrial antibody IgG subclass distribution and affinity in primary biliary cirrhosis.原发性胆汁性肝硬化中抗线粒体抗体IgG亚类分布及亲和力
Clin Exp Immunol. 1992 Apr;88(1):56-61. doi: 10.1111/j.1365-2249.1992.tb03039.x.