Webster L A, Layde P M, Wingo P A, Ory H W
Lancet. 1983 Sep 24;2(8352):724-6. doi: 10.1016/s0140-6736(83)92258-4.
To investigate whether women who consume alcoholic beverages have a greater risk of breast cancer than women who never drink data from a population-based, case-control study, the Centers for Disease Control's Cancer and Steroid Hormone Study, were examined. During the first 15 months of data collection, 1226 women aged 20--54 with newly diagnosed breast cancer and 1279 women of the same age randomly selected from the general population were interviewed. Women who consumed alcoholic beverages had no greater risk of breast cancer than non-drinkers (relative risk 1.0, 95% confidence interval 0.8--1.2). Breast-cancer risk was not associated with the average amount of alcohol consumed per week nor with the type of alcoholic beverage consumed. Compared with non-drinkers, the relative risks of breast cancer for women who ever drank beer, wine, or spirits were 1.0, 0.8, and 0.9, respectively.
为了调查饮用酒精饮料的女性患乳腺癌的风险是否高于从不饮酒的女性，我们研究了疾病控制中心开展的一项基于人群的病例对照研究——癌症与类固醇激素研究的数据。在数据收集的前15个月，对1226名年龄在20至54岁之间、新诊断为乳腺癌的女性以及从普通人群中随机挑选的1279名同年龄段女性进行了访谈。饮用酒精饮料的女性患乳腺癌的风险并不高于不饮酒者（相对风险为1.0，95%置信区间为0.8至1.2）。乳腺癌风险与每周平均饮酒量以及饮用的酒精饮料类型均无关。与不饮酒者相比，曾经饮用啤酒、葡萄酒或烈酒的女性患乳腺癌的相对风险分别为1.0、0.8和0.9。
