Schreck C E, Haile D G, Kline D L
Am J Trop Med Hyg. 1984 Jul;33(4):725-30. doi: 10.4269/ajtmh.1984.33.725.
Field tests were conducted to compare the degree of protection from bites by the mosquito Aedes taeniorhynchus (Wiedemann) provided by wearing clothing treated with permethrin [(3-phenoxyphenyl)methyl (+/-) cis/trans 3-(2-dichloroethenyl)2, 2-dimethylcyclopropanecarboxylate] with that provided by applying deet (N,N-diethyl-m-toluamide) to exposed skin or by applying deet and wearing the treated clothing. Human test subjects were exposed to natural populations of mosquitoes for a 9-hour daytime period (total of 8 days/treatment) while using one or both protection methods. Unprotected test subjects were also exposed for short periods each day as a check to determine the overall biting rate of mosquitoes. The combined use of both protection methods was the most effective treatment in preventing bites, resulting in an average of 1.5 bites/9-hour day, compared with 53.5 and 98.5 bites on subjects protected only with treated clothing or deet, respectively, and 2,287 bites (extrapolated) on subjects who wore untreated clothing during the same time period. Measurements also indicated that the toxic effect of permethrin reduced biting rates by greater than 90% within the immediate area where subjects wore permethrin-treated uniforms for 9 hours.
进行了现场试验,以比较穿着用氯菊酯[(3 - 苯氧基苯基)甲基(±)顺式/反式3 - (2 - 二氯乙烯基)-2,2 - 二甲基环丙烷羧酸酯]处理的衣物、在暴露皮肤上涂抹避蚊胺(N,N - 二乙基 - m - 甲苯酰胺)或同时涂抹避蚊胺并穿着经处理的衣物所提供的对致倦库蚊(维德曼)叮咬的防护程度。人体试验对象在白天9小时内(每种处理共8天)暴露于自然蚊虫种群中,同时使用一种或两种防护方法。未受保护的试验对象每天也会短时间暴露,作为对照以确定蚊虫的总体叮咬率。两种防护方法联合使用是预防叮咬最有效的处理方式,平均每天9小时有1.5次叮咬,相比之下,仅穿着经处理衣物或仅涂抹避蚊胺的试验对象分别有53.5次和98.5次叮咬,而在同一时间段内穿着未处理衣物的试验对象有2287次叮咬(推算值)。测量还表明,在试验对象穿着经氯菊酯处理的制服9小时的直接区域内,氯菊酯的毒性作用使叮咬率降低了90%以上。