犬十二指肠-胃反流对生长抑素释放的抑制作用。
Suppression of somatostatin release by duodenogastric reflux in dogs.
作者信息
Thomas W E, Ardill J, Buchanan K D
出版信息
Gut. 1984 Nov;25(11):1230-3. doi: 10.1136/gut.25.11.1230.
Abstract
The effect of duodenogastric reflux on systemic and portal venous blood concentrations of somatostatin has been studied in the dog. Duodenogastric reflux suppressed somatostatin concentrations in both systemic and portal venous blood, but this did not occur when bile alone was diverted into the stomach. The suppression was also much less marked when truncal vagotomy accompanied the reflux. These findings suggest that altered somatostatin activity may play a part in the production of the pathophysiological changes occurring in clinical conditions such as peptic ulceration, in which there is an increase in duodenogastric reflux.
摘要
十二指肠-胃反流对犬体循环和门静脉血中生长抑素浓度的影响已得到研究。十二指肠-胃反流可抑制体循环和门静脉血中生长抑素的浓度，但单纯将胆汁引流至胃内时则不会出现这种情况。当迷走神经干切断术与反流同时存在时，这种抑制作用也明显减弱。这些发现提示，生长抑素活性的改变可能在诸如消化性溃疡等临床疾病所发生的病理生理变化中起作用，在这些疾病中十二指肠-胃反流增加。
相似文献
1
Suppression of somatostatin release by duodenogastric reflux in dogs.犬十二指肠-胃反流对生长抑素释放的抑制作用。
Gut. 1984 Nov;25(11):1230-3. doi: 10.1136/gut.25.11.1230.
2
[Influence of post-vagotomy duodenogastric reflux on gastric mucosal structure].[迷走神经切断术后十二指肠-胃反流对胃黏膜结构的影响]
Nihon Geka Gakkai Zasshi. 1985 Jun;86(6):686-96.
3
The hormonal changes produced by duodenogastric reflux.十二指肠-胃反流产生的激素变化。
Scand J Gastroenterol Suppl. 1984;92:44-7.
4
Cholecystectomy and truncal vagotomy with pyloroplasty. The effect on duodenogastric reflux.胆囊切除术及迷走神经干切断术加幽门成形术。对十二指肠胃反流的影响。
S Afr Med J. 1987 Feb 21;71(4):239-41.
5
The effect of secretin on duodenogastric reflux in vagotomised dogs.促胰液素对迷走神经切断术后犬十二指肠-胃反流的影响。
S Afr Med J. 1987 Oct 3;72(7):499-500.
6
Effect of truncal vagotomy on functional and morphological changes produced by duodenogastric reflux.迷走神经干切断术对十二指肠-胃反流所致功能和形态学改变的影响。
Dig Dis Sci. 1982 Jul;27(7):609-14. doi: 10.1007/BF01297217.
7
[Duodenogastric reflux--a current evaluation].[十二指肠-胃反流——当前评估]
Zentralbl Chir. 1985;110(5):257-70.
8
Relationship between antropyloric and intestinal motility and duodenogastric reflux in fasting dogs.空腹犬胃幽门与肠道蠕动及十二指肠胃反流之间的关系
Dig Dis Sci. 1987 Feb;32(2):171-6. doi: 10.1007/BF01297105.
9
Inhibitory effect of somatostatin on gastric acid secretion and serum gastrin in dogs with and without duodenogastric reflux.生长抑素对伴有和不伴有十二指肠-胃反流犬胃酸分泌及血清胃泌素的抑制作用
Gut. 1980 Nov;21(11):996-1001. doi: 10.1136/gut.21.11.996.
10
[Duodenogastric reflux in gastric and duodenal peptic ulcer].[胃及十二指肠消化性溃疡中的十二指肠胃反流]
Klin Med (Mosk). 1984 Jun;62(6):31-7.
引用本文的文献
1
Mucosal distribution of somatostatin-secreting gastric Delta cells in children with gastrointestinal reflux diseases.胃泌素分泌性胃δ细胞在儿童胃食管反流病中的黏膜分布
Front Pediatr. 2023 Oct 20;11:1275842. doi: 10.3389/fped.2023.1275842. eCollection 2023.
2
Increased Risk of Peptic Ulcers Following a Cholecystectomy for Gallstones.胆囊结石胆囊切除术后消化性溃疡风险增加。
Sci Rep. 2016 Jul 29;6:30702. doi: 10.1038/srep30702.
本文引用的文献
1
Functional changes in acid secretion produced by duodenogastric reflux.十二指肠-胃反流引起的胃酸分泌功能变化。
Gut. 1980 May;21(5):413-7. doi: 10.1136/gut.21.5.413.
2
Gastric morphological and functional changes produced by bile in the canine stomach.胆汁对犬胃造成的胃形态学和功能变化。
Eur Surg Res. 1981;13(2):125-33. doi: 10.1159/000128178.
3
The effect of duodeno-gastric reflux on serum gastrin levels in the dog.十二指肠-胃反流对犬血清胃泌素水平的影响。
Eur Surg Res. 1980;12(6):403-7. doi: 10.1159/000128147.
4
Bile acid and lysolecithin concentrations in the stomach in patients with duodenal ulcer before operation and after treatment by highly selective vagotomy, partial gastrectomy, or truncal vagotomy and drainage.十二指肠溃疡患者在手术前以及经高选择性迷走神经切断术、胃部分切除术或迷走神经干切断术加引流术治疗后的胃内胆汁酸和溶血卵磷脂浓度。
Gut. 1982 Jul;23(7):569-77. doi: 10.1136/gut.23.7.569.
5
Effect of truncal vagotomy on functional and morphological changes produced by duodenogastric reflux.迷走神经干切断术对十二指肠-胃反流所致功能和形态学改变的影响。
Dig Dis Sci. 1982 Jul;27(7):609-14. doi: 10.1007/BF01297217.
6
Antral gastrin-producing G-cells and somatostatin-producing D-cells in different states of gastric acid secretion.处于不同胃酸分泌状态下的胃窦部产胃泌素G细胞和产生长抑素D细胞。
Gut. 1982 Apr;23(4):285-91. doi: 10.1136/gut.23.4.285.
7
The kinetics of somatostatin inhibition of gastric acid secretion.生长抑素抑制胃酸分泌的动力学。
Regul Pept. 1980 Dec;1(3):245-51. doi: 10.1016/0167-0115(80)90274-8.
8
Inhibitory effect of somatostatin on gastric acid secretion and serum gastrin in dogs with and without duodenogastric reflux.生长抑素对伴有和不伴有十二指肠-胃反流犬胃酸分泌及血清胃泌素的抑制作用
Gut. 1980 Nov;21(11):996-1001. doi: 10.1136/gut.21.11.996.
9
Duodeno-gastric reflux--a common factor in pathogenesis of gastric and duodenal ulcer.十二指肠-胃反流——胃及十二指肠溃疡发病机制中的一个常见因素。
Lancet. 1980 Nov 29;2(8205):1166-8. doi: 10.1016/s0140-6736(80)92598-2.
10
Increased reflux of bile into the stomach in patients with gastric ulcer.胃溃疡患者胆汁反流至胃内的情况增加。
Gastroenterology. 1969 Sep;57(3):241-52.
Zotero 插件