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在豚鼠的细胞介导免疫条件下或人类癌症中未能获得阳性的巨噬细胞移动抑制试验结果。

Failure to obtain positive MEM tests in either cell-mediated immune conditions in the guinea-pig or in human cancer.

作者信息

Arvilommi H, Dale M M, Desai H N, Mongar J L, Richardson M

出版信息

Br J Cancer. 1977 Nov;36(5):545-9. doi: 10.1038/bjc.1977.229.

DOI:10.1038/bjc.1977.229
PMID:588418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2025407/
Abstract

The macrophage electrophoretic mobility test described by Caspary and Field (1971) and modified by Pritchard et al. (1973) was investigated in various models of cell-mediated immune conditions in the guinea-pig and in cancer in man. No positive results were obtained in 92 guinea-pig experiments. Only 17 of 154 experiments on 74 patients gave definite positives in experiments with human cancer and a few positive results were obtained with normal healthy subjects.

摘要

由卡斯帕里和菲尔德（1971年）描述并经普里查德等人（1973年）修改的巨噬细胞电泳迁移率试验，在豚鼠细胞介导免疫状况的各种模型以及人类癌症中进行了研究。在92次豚鼠实验中未获得阳性结果。在对74名患者进行的154次实验中，只有17次在人类癌症实验中得到明确阳性结果，而在正常健康受试者中仅获得了一些阳性结果。

相似文献

1
Failure to obtain positive MEM tests in either cell-mediated immune conditions in the guinea-pig or in human cancer.在豚鼠的细胞介导免疫条件下或人类癌症中未能获得阳性的巨噬细胞移动抑制试验结果。
Br J Cancer. 1977 Nov;36(5):545-9. doi: 10.1038/bjc.1977.229.
2
The use of the macrophage electrophoretic mobility test for the diagnosis of eye diseases.巨噬细胞电泳迁移率试验在眼病诊断中的应用。
Mod Probl Ophthalmol. 1976;16:259-64.
3
Evaluation of macrophage electrophoretic mobility (MEM) test as an indicator of cellular immunity in ocular tumours.评估巨噬细胞电泳迁移率（MEM）试验作为眼部肿瘤细胞免疫指标的作用。
Br J Ophthalmol. 1976 Aug;60(8):589-93. doi: 10.1136/bjo.60.8.589.
4
Macrophage electrophoretic mobility (MEM) test in cancer: a critical evaluation.癌症中的巨噬细胞电泳迁移率（MEM）测试：一项批判性评估。
Br J Cancer Suppl. 1973 Aug;1:208-14.
5
Evaluation and development of the macrophage electrophoretic mobility (MEM) test for malignant disease.恶性疾病巨噬细胞电泳迁移率（MEM）检测的评估与开发。
Br J Cancer. 1973 Jan;27(1):1-9. doi: 10.1038/bjc.1973.1.
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Technical aspects of the macrophage electrophoretic mobility (MEM) test for malignant disease.用于恶性疾病的巨噬细胞电泳迁移率（MEM）检测的技术方面。
Br J Cancer Suppl. 1973 Aug;1:229-36.
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Immunological tumour profile: organ-specific carcinoma diagnosis in patients employing the macrophage electrophoretic mobility test.免疫肿瘤谱：采用巨噬细胞电泳迁移率试验对患者进行器官特异性癌诊断。
Cancer Lett. 1977 Jan;2(3):139-45. doi: 10.1016/s0304-3835(77)80003-7.
8
The macrophage electrophoretic mobility (MEM) test for malignant disease. Further clinical investigations and studies on macrophage slowing factors.恶性疾病的巨噬细胞电泳迁移率（MEM）试验。关于巨噬细胞迟缓因子的进一步临床研究
Clin Exp Immunol. 1974 Dec;18(4):543-52.
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Biological and clinical significance of macrophage electrophoretic mobility (MEM) test in tumor immunity.巨噬细胞电泳迁移率（MEM）检测在肿瘤免疫中的生物学及临床意义
Cell Mol Biol Incl Cyto Enzymol. 1979;25(5):355-61.
10
Studies with the macrophage migration inhibition (MMI) test in patients with malignant disease.针对恶性疾病患者进行巨噬细胞游走抑制（MMI）试验的研究。
Clin Exp Immunol. 1975 Nov;22(2):279-84.

引用本文的文献

1
Cell electrophoresis for diagnostic purposes. II. Critical evaluation of conventional cytopherometry.用于诊断目的的细胞电泳。II. 传统细胞电泳术的批判性评价。
Br J Cancer. 1981 May;43(5):598-609. doi: 10.1038/bjc.1981.89.
2
Lymphocyte supernatants and the electrophoretic mobility of erythrocytes: further experience of cancer diagnosis.淋巴细胞上清液与红细胞的电泳迁移率：癌症诊断的进一步经验
Br J Cancer. 1980 Sep;42(3):448-54. doi: 10.1038/bjc.1980.257.
3
Cell electrophoresis for diagnostic purposes. I. Diagnostic value of the electrophoretic mobility test (EMT) for the detection of gynaecological malignancies.用于诊断目的的细胞电泳。I. 电泳迁移率测试（EMT）在检测妇科恶性肿瘤中的诊断价值。
Br J Cancer. 1981 May;43(5):588-97. doi: 10.1038/bjc.1981.88.
4
Reactivity of lymphocytes to basic proteins prepared from brain glioma and stomach cancer with MEM test.采用微量培养试验检测淋巴细胞对脑胶质瘤和胃癌制备的碱性蛋白的反应性。
Br J Cancer. 1981 Apr;43(4):532-6. doi: 10.1038/bjc.1981.76.
5
Effect of lymphocyte supernatants on the electrophoretic mobility of erythrocytes: significance in cancer diagnosis.淋巴细胞上清液对红细胞电泳迁移率的影响：在癌症诊断中的意义
Br J Cancer. 1978 Sep;38(3):401-10. doi: 10.1038/bjc.1978.221.
6
Immunological cross-reactivity between acid extracts of myelin, liver and neoplastic tissues: studies in immunized guinea-pigs.髓磷脂、肝脏和肿瘤组织酸提取物之间的免疫交叉反应性：对免疫豚鼠的研究。
Br J Cancer. 1979 Sep;40(3):424-36. doi: 10.1038/bjc.1979.198.

本文引用的文献

1
AN ENCEPHALITOGENIC PROTEIN OF HUMAN ORIGIN: SOME CHEMICAL AND BIOLOGICAL PROPERTIES.一种人类源致脑炎蛋白：一些化学和生物学特性
Ann N Y Acad Sci. 1965 Mar 31;122:182-98. doi: 10.1111/j.1749-6632.1965.tb20202.x.
2
Technical aspects of the macrophage electrophoretic mobility (MEM) test for malignant disease.用于恶性疾病的巨噬细胞电泳迁移率（MEM）检测的技术方面。
Br J Cancer Suppl. 1973 Aug;1:229-36.
3
Comparison of antigenicity of hepatoma cells, normal liver cells, foetal liver cells and chemically damaged liver cells in guinea-pigs immunized with hepatomata using the macrophage migration inhibition test.用巨噬细胞游走抑制试验比较用肝癌免疫的豚鼠中肝癌细胞、正常肝细胞、胎儿肝细胞及化学损伤肝细胞的抗原性。
Br J Cancer. 1974 Aug;30(2):109-7. doi: 10.1038/bjc.1974.121.
4
Electrophoretic mobility of guinea pig peritoneal exudate cells in hypersensitivity reactions.豚鼠腹膜渗出细胞在超敏反应中的电泳迁移率。
Int Arch Allergy Appl Immunol. 1968;34(3):297-302. doi: 10.1159/000230121.
5
Specific lymphocyte sensitization in cancer: is there a common antigen in human malignant neoplasia?癌症中的特异性淋巴细胞致敏：人类恶性肿瘤中是否存在共同抗原？
Br Med J. 1971 Jun 12;2(5762):613-7. doi: 10.1136/bmj.2.5762.613.