Fulton R W, Pearson N J
Can J Comp Med. 1982 Jan;46(1):100-2.
The interferon inducing ability of bluetongue viruses was studied in bovine and feline monolayer cultures inoculated with each of four bluetongue virus serotypes. Interferon was assayed by a plaque reduction method in monolayer cultures with vesicular stomatitis virus as challenge virus. Interferon was produced by bovine turbinate, Georgia bovine kidney, and Crandell feline kidney monolayer cultures in response to bluetongue virus serotypes 10, 11, 13 and 17. The antiviral substances produced by the bluetongue virus infected cultures had properties of interferon.
在接种了四种蓝舌病毒血清型的牛和猫单层培养物中研究了蓝舌病毒的干扰素诱导能力。采用蚀斑减少法，以水泡性口炎病毒作为攻击病毒，在单层培养物中测定干扰素。牛鼻甲、佐治亚牛肾和克兰德尔猫肾单层培养物在接触蓝舌病毒血清型10、11、13和17后产生了干扰素。蓝舌病毒感染的培养物产生的抗病毒物质具有干扰素的特性。
