Miyazaki M, Watanabe A, Wahid S, Tsunashima M, Sato J
Res Exp Med (Berl). 1982;180(1):15-9. doi: 10.1007/BF01852227.
Serum alpha-fetoprotein (AFP) concentrations increased promptly 2 days following a single injection of DL-ethionine (ethionine) in adult female rats. Continuous elevation of serum AFP was also observed on feeding a diet containing 1% ethionine for at least 2-3 weeks. A rise of serum AFP was not found if the diet was supplemented with 2.8% methionine. Furthermore, in rats fed on 1% ethionine for 2 weeks, dietary change to the laboratory chow supplemented with and without 2.8% methionine produced a decrease of increased serum AFP levels.
成年雌性大鼠单次注射DL-乙硫氨酸（乙硫氨酸）后2天，血清甲胎蛋白（AFP）浓度迅速升高。在喂食含1%乙硫氨酸的饲料至少2 - 3周后，也观察到血清AFP持续升高。如果在饲料中添加2.8%的蛋氨酸，则未发现血清AFP升高。此外，在以1%乙硫氨酸喂养2周的大鼠中，改为喂食添加和不添加2.8%蛋氨酸的实验室常规饲料后，血清AFP升高水平下降。
