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直肠癌治疗中持续保留括约肌策略的长期效果

Long term results of a consistent policy of sphincter preservation in the treatment of carcinoma of the rectum.

作者信息

Jones P F, Thomson H J

出版信息

Br J Surg. 1982 Oct;69(10):564-8. doi: 10.1002/bjs.1800691003.

Abstract

With increasing emphasis on sphincter preservation in the treatment of low carcinomas of the rectum, it is important to know whether such a policy results in satisfactory rectal function and long term survival. In 368 patients operated upon for carcinoma of the rectum between 1958 and 1980, a consistent policy of sphincter preservation was followed, and resulted in 222 (61 per cent) patients having a restorative resection (RR), whilst 132 (37 per cent) had an abdominoperineal excision (APE); 271 (76 per cent) had a radical operation with a hope of cure. Overall operative mortality was 5 per cent (2.6 per cent in the radical group) and the leakage rate in the 222 restorative anastomoses was 5 per cent. Follow-up of 98 per cent of patients treated over 5 years ago has been possible. Special attention has been paid to the late results in patients having a restorative resection of tumours at and below 8 cm: all these patients are continent and there is no excess of late pelvic recurrent. Corrected 5-year survival rates are 72 per cent for abdominoperineal excision and 84 per cent for restorative resection.

摘要

随着在低位直肠癌治疗中对保留括约肌的重视程度不断提高,了解这样的治疗策略是否能带来令人满意的直肠功能和长期生存率就显得尤为重要。在1958年至1980年间接受直肠癌手术的368例患者中,遵循了一致的保留括约肌策略,结果有222例(61%)患者接受了保留肛门括约肌的直肠切除术(RR),而132例(37%)患者接受了腹会阴联合切除术(APE);271例(76%)患者接受了有望治愈的根治性手术。总体手术死亡率为5%(根治性手术组为2.6%),222例保留肛门括约肌的吻合术中吻合口漏发生率为5%。对5年多前接受治疗的98%的患者进行了随访。特别关注了肿瘤位于8厘米及以下且接受保留肛门括约肌直肠切除术患者的远期结果:所有这些患者都能自主控制排便,且盆腔晚期复发率并未增加。腹会阴联合切除术的校正5年生存率为72%,保留肛门括约肌直肠切除术的校正5年生存率为84%。

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