• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

人类抗甲状腺球蛋白抗体上独特个体基因型决定簇及相似个体基因型决定簇的证据。

Evidence of unique idiotypic determinants and similar idiotypic determinants on human antithyroglobulin antibodies.

作者信息

Matsuyama T, Fukumori J, Tanaka H

出版信息

Clin Exp Immunol. 1983 Feb;51(2):381-6.

PMID:6188565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1536903/
Abstract

This is a report on the production of heterologous anti-idiotypic antisera against human anti-thyroglobulin antibodies and on the detection of cross-reactivities among human anti-thyroglobulin antibodies by means of anti-idiotypic antisera. The results are evidence of the existence of unique idiotypic determinant on that anti-thyroglobulin antibody used for immunization and similar idiotypic determinants on all anti-thyroglobulin antibodies.

摘要

这是一篇关于制备针对人抗甲状腺球蛋白抗体的异源抗独特型抗血清以及利用抗独特型抗血清检测人抗甲状腺球蛋白抗体之间交叉反应性的报告。结果证明，用于免疫的抗甲状腺球蛋白抗体上存在独特的独特型决定簇，并且所有抗甲状腺球蛋白抗体上都存在相似的独特型决定簇。

相似文献

1
Evidence of unique idiotypic determinants and similar idiotypic determinants on human antithyroglobulin antibodies.人类抗甲状腺球蛋白抗体上独特个体基因型决定簇及相似个体基因型决定簇的证据。
Clin Exp Immunol. 1983 Feb;51(2):381-6.
2
Cross-reactive idiotypes on high affinity IgG class human monoclonal thyroglobulin autoantibodies.高亲和力IgG类人甲状腺球蛋白单克隆自身抗体上的交叉反应独特型
J Autoimmun. 1993 Feb;6(1):77-91. doi: 10.1006/jaut.1993.1007.
3
The occurrence of defined idiotypes on autoantibodies to mouse thyroglobulin.针对小鼠甲状腺球蛋白自身抗体上特定独特型的出现情况。
Eur J Immunol. 1983 Nov;13(11):942-7. doi: 10.1002/eji.1830131114.
4
Serological analysis of idiotypic determinants on monoclonal antibodies specific to poly(Tyr,Glu)-poly(DLAla)--poly(Lys) and its ordered analogue (Tyr-Tyr-Glu-Glu)-poly(DLAla)--poly(Lys).对聚（酪氨酸，谷氨酸）-聚（D-丙氨酸）-聚（赖氨酸）及其有序类似物（酪氨酸-酪氨酸-谷氨酸-谷氨酸）-聚（D-丙氨酸）-聚（赖氨酸）特异性单克隆抗体独特型决定簇的血清学分析。
Immunology. 1984 Feb;51(2):367-76.
5
Suppression of in vitro human antithyroglobulin antibody secretion by private and cross-reactive anti-idiotypic antibodies.自身及交叉反应性抗独特型抗体对体外人抗甲状腺球蛋白抗体分泌的抑制作用
Clin Immunol Immunopathol. 1986 May;39(2):337-44. doi: 10.1016/0090-1229(86)90097-8.
6
Anti-idiotypic immunity and autoimmunity. I. In vitro and in vivo effects of anti-idiotypic antibodies to spontaneously occurring autoantibodies to rat thyroglobulin.抗独特型免疫与自身免疫。I. 针对大鼠甲状腺球蛋白自发产生的自身抗体的抗独特型抗体的体外和体内效应
Eur J Immunol. 1981 Mar;11(3):187-95. doi: 10.1002/eji.1830110306.
7
Crossreaction of monoclonal antiidiotypic antibodies specific for human antithyroglobulin antibody with the Fc portion of human IgG.对人抗甲状腺球蛋白抗体具有特异性的单克隆抗独特型抗体与人IgG的Fc部分的交叉反应。
J Rheumatol. 1988 Apr;15(4):587-92.
8
Idiotypic determinants on human thyroglobulin autoantibodies derived from the serum of Hashimoto patients and EB virus transformed cell lines.源自桥本氏病患者血清及EB病毒转化细胞系的人甲状腺球蛋白自身抗体的独特型决定簇。
Clin Exp Immunol. 1984 Jul;57(1):33-40.
9
Interspecies cross-reactive determinants of thyroglobulin recognized by autoantibodies.自身抗体识别的甲状腺球蛋白种间交叉反应性决定簇。
Clin Exp Immunol. 1985 Jul;61(1):44-8.
10
Epitope and idiotope mapping using monoclonal antibodies.使用单克隆抗体进行表位和独特型表位图谱分析。
Methods Mol Biol. 1995;51:171-81. doi: 10.1385/0-89603-275-2:171.

引用本文的文献

1
Induction of multinucleated giant cells from rheumatoid arthritis (RA) synovial adherent cells by anti-DR antibody.抗DR抗体诱导类风湿性关节炎（RA）滑膜贴壁细胞形成多核巨细胞。
Clin Exp Immunol. 1994 Nov;98(2):257-63. doi: 10.1111/j.1365-2249.1994.tb06135.x.
2
Idiotypes and autoimmunity.独特型与自身免疫
Springer Semin Immunopathol. 1983;6(1):51-66. doi: 10.1007/BF01857366.
3
Investigation of the idiotypic determinants of IgM monoclonal proteins associated with neuropathy.与神经病变相关的IgM单克隆蛋白独特型决定簇的研究。
Clin Exp Immunol. 1984 Sep;57(3):621-5.
4
Idiotypic determinants on human thyroglobulin autoantibodies derived from the serum of Hashimoto patients and EB virus transformed cell lines.源自桥本氏病患者血清及EB病毒转化细胞系的人甲状腺球蛋白自身抗体的独特型决定簇。
Clin Exp Immunol. 1984 Jul;57(1):33-40.
5
Anti-acetylcholine receptor idiotypes in myasthenia gravis analysed by rabbit anti-sera.用兔抗血清分析重症肌无力中的抗乙酰胆碱受体独特型。
Clin Exp Immunol. 1985 Jun;60(3):637-44.
6
Detection of cross-reactive anti-DNA antibody idiotypes on renal tissue-bound immunoglobulins from lupus patients.狼疮患者肾组织结合免疫球蛋白上交叉反应性抗DNA抗体独特型的检测。
J Clin Invest. 1985 Jul;76(1):287-94. doi: 10.1172/JCI111959.
7
Cross-reactive idiotypes in immunoglobulin A-deficient sera.免疫球蛋白A缺乏血清中的交叉反应独特型
J Clin Invest. 1985 May;75(5):1722-8. doi: 10.1172/JCI111882.
8
Crossreactivity and inheritance of idiotypes restricted to human anti-tetanus toxoid antibodies.局限于人类抗破伤风类毒素抗体的独特型的交叉反应性与遗传性。
J Clin Invest. 1987 Apr;79(4):1242-8. doi: 10.1172/JCI112943.
9
Inherited polymorphism of the human T-cell antigen receptor detected by a monoclonal antibody.通过单克隆抗体检测到的人类T细胞抗原受体的遗传多态性。
Proc Natl Acad Sci U S A. 1986 Oct;83(20):7888-92. doi: 10.1073/pnas.83.20.7888.
10
Long term spectrotypic and idiotypic stability of thyroglobulin autoantibodies in patients with Hashimoto's thyroiditis.桥本甲状腺炎患者甲状腺球蛋白自身抗体的长期光谱型和独特型稳定性
Clin Exp Immunol. 1988 Mar;71(3):459-63.

本文引用的文献

1
Solid-phase radioimmunoassay in antibody-coated tubes.在抗体包被管中的固相放射免疫测定。
Science. 1967 Dec 22;158(3808):1570-2. doi: 10.1126/science.158.3808.1570.
2
Chemical coupling of peptides and proteins to polysaccharides by means of cyanogen halides.通过卤化氰将肽和蛋白质与多糖进行化学偶联。
Nature. 1967 Jun 24;214(5095):1302-4. doi: 10.1038/2141302a0.
3
Antigenic specificities related to the cold agglutinin activity of gamma M globulins.与γM球蛋白冷凝集素活性相关的抗原特异性。
Science. 1968 Jul 26;161(3839):379-81. doi: 10.1126/science.161.3839.379.
4
Idiotype expression and the inheritance of mouse antibody clones.独特型表达与小鼠抗体克隆的遗传
J Exp Med. 1973 Mar 1;137(3):603-21. doi: 10.1084/jem.137.3.603.
5
Cross-idiotypic specificity among monoclonal IgM proteins with anti- -globulin activity.具有抗球蛋白活性的单克隆IgM蛋白之间的交叉独特型特异性。
J Exp Med. 1973 Feb 1;137(2):331-42. doi: 10.1084/jem.137.2.331.
6
Evidence of similar idiotypic determinants on different rheumatoid factor populations.不同类风湿因子群体上相似独特型决定簇的证据。
Scand J Immunol. 1979 Mar;9(3):281-9. doi: 10.1111/j.1365-3083.1979.tb02732.x.
7
Immunoreactive properties of anti-thyroglobulin autoantibodies isolated by affinity chromatography from human thyroiditis serum.通过亲和层析从人类甲状腺炎血清中分离出的抗甲状腺球蛋白自身抗体的免疫反应特性。
Clin Exp Immunol. 1978 Feb;31(2):218-25.