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风湿性多肌痛和巨细胞动脉炎:循环免疫复合物

Polymyalgia rheumatica and giant cell arteritis: circulating immune complexes.

作者信息

Espinoza L R, Bridgeford P, Lowenstein M, Bocanegra T S, Vasey F B, Germain B F

出版信息

J Rheumatol. 1982 Jul-Aug;9(4):556-60.

PMID:6215486
Abstract

Circulating immune complexes (CIC) were detected in a large population of patients with polymyalgia rheumatica (PMR) alone, PMR-giant cell arteritis (GCA), and GCA alone. CIC were found in the majority of patients studied. A direct correlation was observed between levels of CIC material and the erythrocyte sedimentation rate. The presence of immune complexes in the sera of patients with these disorders do not have diagnostic significance but may play an important role in their pathogenesis.

摘要

在大量仅患有风湿性多肌痛(PMR)、PMR-巨细胞动脉炎(GCA)以及仅患有GCA的患者群体中检测到循环免疫复合物(CIC)。在所研究的大多数患者中都发现了CIC。观察到CIC物质水平与红细胞沉降率之间存在直接相关性。这些疾病患者血清中免疫复合物的存在虽不具有诊断意义,但可能在其发病机制中起重要作用。

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Polymyalgia rheumatica and giant cell arteritis: circulating immune complexes.风湿性多肌痛和巨细胞动脉炎:循环免疫复合物
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引用本文的文献

1
In vitro cytotoxicity of human endothelial cells in polymyalgia rheumatica and giant cell arteritis.风湿性多肌痛和巨细胞动脉炎中人类内皮细胞的体外细胞毒性
Rheumatol Int. 1982;2(3):133-6. doi: 10.1007/BF00541166.
2
Selective depletion and activation of CD8+ lymphocytes from peripheral blood of patients with polymyalgia rheumatica and giant cell arteritis.从风湿性多肌痛和巨细胞动脉炎患者外周血中选择性消耗和激活CD8 +淋巴细胞。
Ann Rheum Dis. 1989 Apr;48(4):307-11. doi: 10.1136/ard.48.4.307.
3
Antibodies to intermediate filaments in polymyalgia rheumatica and giant cell arteritis: a sequential study.
风湿性多肌痛和巨细胞动脉炎中中间丝抗体的序贯研究。
Ann Rheum Dis. 1987 Oct;46(10):746-9. doi: 10.1136/ard.46.10.746.