从持续感染水疱性口炎病毒的细胞中分离出的病毒，与缺陷干扰颗粒的相互作用发生了改变。
Viruses isolated from cells persistently infected with vesicular stomatitis virus show altered interactions with defective interfering particles.
作者信息
Horodyski F M, Holland J J
出版信息
J Virol. 1980 Nov;36(2):627-31. doi: 10.1128/JVI.36.2.627-631.1980.
Abstract
Virus mutants isolated from persistent infections of vesicular stomatitis virus in BHK-21 cells were much less susceptible to interference mediated by the defective interfering particle used to establish the persistent infection. This mutational change occurred as early as 34 days in the persistent infection and continued for over 5 years. The earliest variants showed no oligonucleotide map changes and no difference in the temperature-sensitive phenotype from the original virus, but the later variants exhibited extensive map changes. These results suggest a possible role for defective interfering particles in the selection of the mutants.
摘要
从水泡性口炎病毒在BHK - 21细胞中的持续感染中分离出的病毒突变体，对用于建立持续感染的缺陷干扰颗粒介导的干扰作用的敏感性要低得多。这种突变变化早在持续感染的第34天就出现了，并持续了5年多。最早的变体在寡核苷酸图谱上没有变化，温度敏感表型与原始病毒也没有差异，但后来的变体表现出广泛的图谱变化。这些结果表明缺陷干扰颗粒在突变体的选择中可能起作用。
相似文献
1
Viruses isolated from cells persistently infected with vesicular stomatitis virus show altered interactions with defective interfering particles.
J Virol. 1980 Nov;36(2):627-31. doi: 10.1128/JVI.36.2.627-631.1980.
2
Reconstruction experiments demonstrating selective effects of defective interfering particles on mixed populations of vesicular stomatitis virus.
J Gen Virol. 1984 Apr;65 ( Pt 4):819-23. doi: 10.1099/0022-1317-65-4-819.
3
Defective interfering particles of vesicular stomatitis virus: structure-function relationships.
Ann N Y Acad Sci. 1980;354:238-50. doi: 10.1111/j.1749-6632.1980.tb27970.x.
4
Persistent vesicular stomatitis virus infection mediates base substitutions in viral RNA termini.
J Virol. 1979 Nov;32(2):420-8. doi: 10.1128/JVI.32.2.420-428.1979.
5
Effect of defective interfering particles on plus- and minus- strand leader RNAs in vesicular stomatitis virus-infected cells.
J Virol. 1980 Sep;35(3):704-9. doi: 10.1128/JVI.35.3.704-709.1980.
6
Continuing coevolution of virus and defective interfering particles and of viral genome sequences during undiluted passages: virus mutants exhibiting nearly complete resistance to formerly dominant defective interfering particles.
J Virol. 1987 Feb;61(2):454-64. doi: 10.1128/JVI.61.2.454-464.1987.
7
Inhibition of vesicular stomatitis virus-defective interfering particle synthesis by Shope fibroma virus.
Virology. 1979 Mar;93(2):515-26. doi: 10.1016/0042-6822(79)90254-x.
8
Ultraviolet-irradiated vesicular stomatitis virus and defective-interfering particles are similar non-specific inhibitors of virus infection.
J Gen Virol. 1982 Jun;60(Pt 2):327-33. doi: 10.1099/0022-1317-60-2-327.
9
The intracellular half-lives of nonreplicating nucleocapsids of DI particles of wild type and mutant strains of vesicular stomatitis virus.
Virology. 1986 Jun;151(2):371-8. doi: 10.1016/0042-6822(86)90057-7.
10
Altered replicase specificity is responsible for resistance to defective interfering particle interference of an Sdi- mutant of vesicular stomatitis virus.
J Virol. 1988 Oct;62(10):3614-21. doi: 10.1128/JVI.62.10.3614-3621.1988.
引用本文的文献
1
A measles virus collective infectious unit that caused lethal human brain disease includes many locally restricted and few widespread copy-back defective genomes.
J Virol. 2024 Nov 19;98(11):e0123224. doi: 10.1128/jvi.01232-24. Epub 2024 Oct 21.
2
Repeatable Population Dynamics among Vesicular Stomatitis Virus Lineages Evolved under High Co-infection.
Front Microbiol. 2016 Mar 31;7:370. doi: 10.3389/fmicb.2016.00370. eCollection 2016.
3
Defective interfering influenza virus RNAs: time to reevaluate their clinical potential as broad-spectrum antivirals?
J Virol. 2014 May;88(10):5217-27. doi: 10.1128/JVI.03193-13. Epub 2014 Feb 26.
4
Design requirements for interfering particles to maintain coadaptive stability with HIV-1.
J Virol. 2013 Feb;87(4):2081-93. doi: 10.1128/JVI.02741-12. Epub 2012 Dec 5.
5
Defective interfering influenza virus confers only short-lived protection against influenza virus disease: evidence for a role for adaptive immunity in DI virus-mediated protection in vivo.
Vaccine. 2011 Sep 2;29(38):6584-91. doi: 10.1016/j.vaccine.2011.06.114. Epub 2011 Jul 14.
6
Defective interfering particles of Sindbis virus do not interfere with the homologous virus obtained from persistently infected BHK cells but do interfere with Semliki Forest virus.
J Virol. 1981 Feb;37(2):840-4. doi: 10.1128/JVI.37.2.840-844.1981.
7
Evolution of virus and defective-interfering RNAs in BHK cells persistently infected with Sindbis virus.
J Virol. 1983 Dec;48(3):676-84. doi: 10.1128/JVI.48.3.676-684.1983.
8
Vesicular stomatitis virus mutants resistant to defective-interfering particles accumulate stable 5'-terminal and fewer 3'-terminal mutations in a stepwise manner.
J Virol. 1984 Mar;49(3):793-8. doi: 10.1128/JVI.49.3.793-798.1984.
9
Continuing coevolution of virus and defective interfering particles and of viral genome sequences during undiluted passages: virus mutants exhibiting nearly complete resistance to formerly dominant defective interfering particles.
J Virol. 1987 Feb;61(2):454-64. doi: 10.1128/JVI.61.2.454-464.1987.
10
Molecular basis for interference of defective interfering particles of pseudorabies virus with replication of standard virus.
J Virol. 1986 Aug;59(2):308-17. doi: 10.1128/JVI.59.2.308-317.1986.
本文引用的文献
1
BIOLOGIC PROPERTIES OF TWO PLAQUE VARIANTS OF VESICULAR STOMATITIS VIRUS (INDIANA SEROTYPE).
J Immunol. 1963 Jul;91:112-22.
2
Some properties of the transmissible interfering component of vesicular stomatitis virus preparations.
J Gen Microbiol. 1959 Dec;21:498-509. doi: 10.1099/00221287-21-3-498.
3
Establishment and maintenance of persistent infection by Sindbis virus in BHK cells.
J Virol. 1980 Jan;33(1):463-74. doi: 10.1128/JVI.33.1.463-474.1980.
4
Semliki forest virus persistence in mouse L929 cells.
Virology. 1980 Jan 15;100(1):141-55. doi: 10.1016/0042-6822(80)90560-7.
5
Virus protein changes and RNA termini alterations evolving during persistent infection.
Cell. 1980 Apr;19(4):871-80. doi: 10.1016/0092-8674(80)90078-1.
6
Defective viral particles and viral disease processes.
Nature. 1970 Apr 25;226(5243):325-7. doi: 10.1038/226325a0.
7
Temperature-sensitive defect of mutants isolated from L cells persistently infected with Newcastle disease virus.
J Virol. 1973 Sep;12(3):472-80. doi: 10.1128/JVI.12.3.472-480.1973.
8
Persistent noncytocidal vesicular stomatitis virus infections mediated by defective T particles that suppress virion transcriptase.
Proc Natl Acad Sci U S A. 1974 Aug;71(8):2956-60. doi: 10.1073/pnas.71.8.2956.
9
Natural selection of mutants of vesicular stomatitis virus by cultured cells of Drosophila melanogaster.
J Gen Virol. 1973 Sep;20(3):341-51. doi: 10.1099/0022-1317-20-3-341.
10
Prophylaxis and immunization in mice by use of virus-free defective T particles to protect against intracerebral infection by vesicular stomatitis virus.
Proc Natl Acad Sci U S A. 1973 Jul;70(7):2105-8. doi: 10.1073/pnas.70.7.2105.
Zotero 插件