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Nucleotide sequence of the gene ompA coding the outer membrane protein II of Escherichia coli K-12.编码大肠杆菌K-12外膜蛋白II的ompA基因的核苷酸序列。
Nucleic Acids Res. 1980 Jul 11;8(13):3011-27. doi: 10.1093/nar/8.13.3011.
2
The nucleotide sequence coding for major outer membrane protein OmpA of Shigella dysenteriae.编码痢疾志贺氏菌主要外膜蛋白OmpA的核苷酸序列。
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Role of enteric bacteria in the pathogenesis of rheumatoid arthritis: evidence for antibodies to enterobacterial common antigens in rheumatoid sera and synovial fluids.肠道细菌在类风湿关节炎发病机制中的作用：类风湿血清和滑液中存在抗肠道细菌共同抗原抗体的证据。
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本文引用的文献

1
Amino acid sequence of the signal peptide of ompA protein, a major outer membrane protein of Escherichia coli.大肠杆菌主要外膜蛋白ompA蛋白信号肽的氨基酸序列。
J Biol Chem. 1980 Jan 10;255(1):27-9.
2
Messenger ribonucleic acid of the lipoprotein of the Escherichia coli outer membrane. II. The complete nucleotide sequence.大肠杆菌外膜脂蛋白的信使核糖核酸。II. 完整核苷酸序列。
J Biol Chem. 1980 Jan 10;255(1):210-6.
3
Con--mutants: class of mutants in Escherichia coli K-12 lacking a major cell wall protein and defective in conjugation and adsorption of a bacteriophage.Con突变体：大肠杆菌K-12中的一类突变体，缺乏一种主要的细胞壁蛋白，在噬菌体的接合和吸附方面存在缺陷。
J Bacteriol. 1974 Sep;119(3):726-35. doi: 10.1128/jb.119.3.726-735.1974.
4
Cell envelope and shape of Escherichia coli K12. The ghost membrane.大肠杆菌K12的细胞包膜与形态。空细胞膜。
Eur J Biochem. 1973 Nov 1;39(1):27-36. doi: 10.1111/j.1432-1033.1973.tb03099.x.
5
Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol.氯霉素存在下大肠杆菌中Col E 1质粒复制的性质
J Bacteriol. 1972 May;110(2):667-76. doi: 10.1128/jb.110.2.667-676.1972.
6
The major proteins of the Escherichia coli outer cell envelope membrane. Characterization of proteins II* and III, comparison of all proteins.大肠杆菌外细胞膜的主要蛋白质。蛋白质II*和III的特性，所有蛋白质的比较。
Eur J Biochem. 1975 Nov 1;59(1):215-21. doi: 10.1111/j.1432-1033.1975.tb02444.x.
7
Mapping and characterization of promoters in bacteriophages fd, f1 and m13.噬菌体fd、f1和m13中启动子的定位与表征
J Mol Biol. 1975 Feb 25;92(2):261-77. doi: 10.1016/0022-2836(75)90226-0.
8
The major proteins of the Excherichia coli outer cell envelope membrane. Preparative isolation of all major membrane proteins.
Eur J Biochem. 1975 Nov 1;59(1):207-13. doi: 10.1111/j.1432-1033.1975.tb02443.x.
9
Restriction endonucleases.限制性内切核酸酶
CRC Crit Rev Biochem. 1976 Nov;4(2):123-64. doi: 10.3109/10409237609105456.
10
A simple method for DNA restriction site mapping.一种用于DNA限制性酶切位点图谱绘制的简单方法。
Nucleic Acids Res. 1976 Sep;3(9):2387-98. doi: 10.1093/nar/3.9.2387.

编码大肠杆菌K-12外膜蛋白II的ompA基因的核苷酸序列。

Nucleotide sequence of the gene ompA coding the outer membrane protein II of Escherichia coli K-12.

作者信息

Beck E, Bremer E

出版信息

Nucleic Acids Res. 1980 Jul 11;8(13):3011-27. doi: 10.1093/nar/8.13.3011.

DOI:10.1093/nar/8.13.3011
PMID:6253901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC324141/
Abstract

A nucleotide sequence of 2271 basepairs has been determined from cloned E. coli DNA which contains ompA. Withing that sequence, starting at nucleotide 1037, an open translational reading frame encodes a protein of 367 amino acids which starting with amino acid 22 agrees with the primary structure of protein II. The preceeding 21 amino acids constitute a typical signal sequence. There is a non-translated region of 360 nucleotides in front of the translational start. The insertion point of an IS1 element 110 nucleotides upstream from the start codon and an amber codon at the position of amino acid residue 28 have been localized in the DNA from two ompA mutants.

摘要

已从含有ompA的克隆大肠杆菌DNA中确定了一段2271个碱基对的核苷酸序列。在该序列中，从核苷酸1037开始，一个开放的翻译阅读框编码一个由367个氨基酸组成的蛋白质，该蛋白质从第22个氨基酸开始与蛋白质II的一级结构一致。前面的21个氨基酸构成一个典型的信号序列。在翻译起始位点之前有一个360个核苷酸的非翻译区。在两个ompA突变体的DNA中，已定位了一个位于起始密码子上游110个核苷酸处的IS1元件的插入点以及位于氨基酸残基28位置的一个琥珀密码子。