黑腹果蝇热休克激活基因的核苷酸序列。I. 杂交质粒56H8中hsp 70基因5'和3'末端区域的序列。

Nucleotide sequences of heat shock activated genes in Drosophila melanogaster. I. Sequences in the regions of the 5' and 3' ends of the hsp 70 gene in the hybrid plasmid 56H8.

作者信息

Török I, Karch F

出版信息

Nucleic Acids Res. 1980 Jul 25;8(14):3105-23. doi: 10.1093/nar/8.14.3105.

DOI:10.1093/nar/8.14.3105

PMID:6255408

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC324358/

Abstract

We present the sequences at the 5' and 3' ends of one hsp 70 gene variant which is derived from the chromosomal locus 87A7. The 5' end of the hsp 70 mRNA has also been determined. 550 bp upstream from the 5' end of the hsp 70 mRNA, there is a very A+T rich region shown by heteroduplex analysis to be also present at the same position in other hsp 70 genes9. The 5' end of the hsp 70 mRNA was found 26 bp after a characteristic "Hogness box". The first ATG codon was found 250 bp downstream from the 5' end of the hsp 70 mRNA. We also determined the termination codon at the 3' end of the hsp 70 gene. Comparisons with other genes are discussed.

摘要

我们展示了一个源自染色体位点87A7的热休克蛋白70（hsp 70）基因变体5'和3'端的序列。hsp 70信使核糖核酸（mRNA）的5'端也已确定。在hsp 70 mRNA 5'端上游550碱基对（bp）处，有一个富含腺嘌呤（A）和胸腺嘧啶（T）的区域，异源双链分析显示该区域在其他hsp 70基因的相同位置也存在。hsp 70 mRNA的5'端在一个特征性的“霍格内斯盒”后26 bp处被发现。第一个甲硫氨酸（ATG）密码子在hsp 70 mRNA 5'端下游250 bp处被发现。我们还确定了hsp 70基因3'端的终止密码子。文中讨论了与其他基因的比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ab4/324358/474485e49e69/nar00431-0053-a.jpg

相似文献

Nucleotide sequences of heat shock activated genes in Drosophila melanogaster. I. Sequences in the regions of the 5' and 3' ends of the hsp 70 gene in the hybrid plasmid 56H8.

Nucleic Acids Res. 1980 Jul 25;8(14):3105-23. doi: 10.1093/nar/8.14.3105.

Four heat shock proteins of Drosophila melanogaster coded within a 12-kilobase region in chromosome subdivision 67B.

Proc Natl Acad Sci U S A. 1980 Sep;77(9):5390-3. doi: 10.1073/pnas.77.9.5390.

DNA sequences flanking the starts of the hsp 70 and alpha beta heat shock genes are homologous.

Dev Biol. 1981 Apr 30;83(2):291-300. doi: 10.1016/0012-1606(81)90475-9.

Primary sequence of the 5' flanking regions of the Drosophila heat shock genes in chromosome subdivision 67B.

Nucleic Acids Res. 1981 Apr 10;9(7):1627-42. doi: 10.1093/nar/9.7.1627.

Sequence of three copies of the gene for the major Drosophila heat shock induced protein and their flanking regions.

Cell. 1980 Oct;21(3):669-79. doi: 10.1016/0092-8674(80)90430-4.

Two hybrid plasmids with D. melanogaster DNA sequences complementary to mRNA coding for the major heat shock protein.

Cell. 1978 Aug;14(4):921-9. doi: 10.1016/0092-8674(78)90346-x.

Localization of the hsp83 transcript within a 3292 nucleotide sequence from the 63B heat shock locus of D. melanogaster.

Nucleic Acids Res. 1983 Oct 25;11(20):7011-30. doi: 10.1093/nar/11.20.7011.

DNase I hypersensitive sites in Drosophila chromatin occur at the 5' ends of regions of transcription.

Proc Natl Acad Sci U S A. 1981 Jan;78(1):143-6. doi: 10.1073/pnas.78.1.143.

The sequence of the Drosophila melanogaster gene for yolk protein 1.

Nucleic Acids Res. 1981 Dec 11;9(23):6407-19. doi: 10.1093/nar/9.23.6407.

Genetic and molecular analysis of the 87A7 and 87C1 heat-inducible loci of D. melanogaster.

Cell. 1979 Dec;18(4):1351-8. doi: 10.1016/0092-8674(79)90245-9.

引用本文的文献

Transferable approaches to CRISPR-Cas9 induced genome editing in non-model insects: a brief guide.

Front Zool. 2025 Jul 7;22(1):13. doi: 10.1186/s12983-025-00566-2.

The Binding of CSL Proteins to Either Co-Activators or Co-Repressors Protects from Proteasomal Degradation Induced by MAPK-Dependent Phosphorylation.

Int J Mol Sci. 2022 Oct 15;23(20):12336. doi: 10.3390/ijms232012336.

White spot syndrome virus annexes a shrimp STAT to enhance expression of the immediate-early gene ie1.

J Virol. 2007 Feb;81(3):1461-71. doi: 10.1128/JVI.01880-06. Epub 2006 Nov 1.

DNA sequence analysis reveals extensive homologies of regions preceding hsp70 and alphabeta heat shock genes in Drosophila melanogaster.

Proc Natl Acad Sci U S A. 1981 Oct;78(10):6196-200. doi: 10.1073/pnas.78.10.6196.

The baculovirus PE38 protein augments apoptosis induced by transactivator IE1.

J Virol. 1999 Aug;73(8):6691-9. doi: 10.1128/JVI.73.8.6691-6699.1999.

Nineteen baculovirus open reading frames, including LEF-12, support late gene expression.

J Virol. 1998 Dec;72(12):10197-206. doi: 10.1128/JVI.72.12.10197-10206.1998.

Role of baculovirus IE2 and its RING finger in cell cycle arrest.

J Virol. 1998 Jan;72(1):684-92. doi: 10.1128/JVI.72.1.684-692.1998.

Doom, a product of the Drosophila mod(mdg4) gene, induces apoptosis and binds to baculovirus inhibitor-of-apoptosis proteins.

Mol Cell Biol. 1997 May;17(5):2835-43. doi: 10.1128/MCB.17.5.2835.

Induction of apoptosis by baculovirus transactivator IE1.

J Virol. 1996 Oct;70(10):7116-24. doi: 10.1128/JVI.70.10.7116-7124.1996.

In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes.

Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):7923-7. doi: 10.1073/pnas.90.17.7923.

本文引用的文献

Ubiquitous and gene-specific regulatory 5' sequences in a sea urchin histone DNA clone coding for histone protein variants.

Nucleic Acids Res. 1980 Mar 11;8(5):957-77. doi: 10.1093/nar/8.5.957.

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

Proc Natl Acad Sci U S A. 1980 Mar;77(3):1432-6. doi: 10.1073/pnas.77.3.1432.

Two genes for the major heat-shock protein of Drosophila melanogaster arranged as an inverted repeat.

Nucleic Acids Res. 1980 Jan 25;8(2):235-52. doi: 10.1093/nar/8.2.235.

The ovalbumin gene-sequence of putative control regions.

Nucleic Acids Res. 1980 Jan 11;8(1):127-42. doi: 10.1093/nar/8.1.127.

Fragments produced by cleavage of lambda deoxyribonucleic acid with the Hemophilus parainfluenzae restriction enzyme Hpa II.

Biochemistry. 1973 Sep 25;12(20):3972-7. doi: 10.1021/bi00744a029.

Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs.

J Mol Biol. 1974 Apr 15;84(3):389-98. doi: 10.1016/0022-2836(74)90447-1.

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Cell. 1977 Nov;12(3):721-32. doi: 10.1016/0092-8674(77)90272-0.

3' non-coding region sequences in eukaryotic messenger RNA.

Nature. 1976 Sep 16;263(5574):211-4. doi: 10.1038/263211a0.

A simple method for DNA restriction site mapping.

Nucleic Acids Res. 1976 Sep;3(9):2387-98. doi: 10.1093/nar/3.9.2387.

Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit.

Cell. 1978 Dec;15(4):1463-75. doi: 10.1016/0092-8674(78)90070-3.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

黑腹果蝇热休克激活基因的核苷酸序列。I. 杂交质粒56H8中hsp 70基因5'和3'末端区域的序列。

Nucleotide sequences of heat shock activated genes in Drosophila melanogaster. I. Sequences in the regions of the 5' and 3' ends of the hsp 70 gene in the hybrid plasmid 56H8.

作者信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

黑腹果蝇热休克激活基因的核苷酸序列。I. 杂交质粒56H8中hsp 70基因5'和3'末端区域的序列。

Nucleotide sequences of heat shock activated genes in Drosophila melanogaster. I. Sequences in the regions of the 5' and 3' ends of the hsp 70 gene in the hybrid plasmid 56H8.

作者信息

出版信息

相似文献

引用本文的文献

本文引用的文献