甲基柔红糖胺对单纯疱疹病毒复制的抑制作用
Inhibition of herpes simplex virus replication by methyl daunosamine.
作者信息
Spivack J G, Prusoff W H, Tritton T R
出版信息
Antimicrob Agents Chemother. 1982 Jul;22(1):176-9. doi: 10.1128/AAC.22.1.176.
Abstract
Methyl daunosamine inhibited the replication of herpes simplex virus type 1 in a dose-dependent manner. The growth of the host Vero cells was not affected by daunosamine levels that had significant antiviral activity (2.5 mM) but was inhibited by concentrations of 5 mM or greater. Methyl daunosamine appears to be unique among the sugars with antiviral activity because at antiviral concentrations it did not inhibit the glycosylation of macromolecules.
摘要
甲基柔红糖胺以剂量依赖的方式抑制单纯疱疹病毒1型的复制。具有显著抗病毒活性（2.5 mM）的柔红糖胺水平不会影响宿主Vero细胞的生长，但5 mM或更高的浓度会抑制其生长。甲基柔红糖胺在具有抗病毒活性的糖类中似乎是独特的，因为在抗病毒浓度下它不会抑制大分子的糖基化。
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本文引用的文献
1
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Cancer Res. 1972 Feb;32(2):380-9.
2
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J Virol. 1974 Jun;13(6):1186-93. doi: 10.1128/JVI.13.6.1186-1193.1974.
3
Effects of 2-deoxy-D-glucose on herpes simplex virus replication.2-脱氧-D-葡萄糖对单纯疱疹病毒复制的影响。
Virology. 1973 Apr;52(2):447-55. doi: 10.1016/0042-6822(73)90340-1.
4
Inhibition of the multiplication of enveloped RNA-viruses by glucosamine and 2-deoxy-D-glucose.氨基葡萄糖和2-脱氧-D-葡萄糖对包膜RNA病毒增殖的抑制作用。
J Gen Virol. 1972 Mar;14(3):251-9. doi: 10.1099/0022-1317-14-3-251.
5
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Nature. 1969 Apr 5;222(5188):36-8. doi: 10.1038/222036a0.
6
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Eur J Biochem. 1976 Nov 1;70(1):55-62. doi: 10.1111/j.1432-1033.1976.tb10955.x.
7
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Eur J Biochem. 1977 Jan;72(2):265-73. doi: 10.1111/j.1432-1033.1977.tb11249.x.
8
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10
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