与斯奈德-泰伦猫肉瘤病毒致癌序列相关的人类基因（c-fes）。

Human gene (c-fes) related to the onc sequences of Snyder-Theilen feline sarcoma virus.

作者信息

Franchini G, Gelmann E P, Dalla-Favera R, Gallo R C, Wong-Staal F

出版信息

Mol Cell Biol. 1982 Aug;2(8):1014-9. doi: 10.1128/mcb.2.8.1014-1019.1982.

DOI:10.1128/mcb.2.8.1014-1019.1982

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC369889/

Abstract

The onc gene (v-fes) of the acutely transforming feline sarcoma virus (Snyder-Theilen strain) has homologous cellular sequences (c-fes) in all vertebrate species, including humans. We isolated from a human DNA library recombinant phages containing overlapping c-fes sequences. The human c-fes locus spans a region of 3.4 kilobases and contains 1.4 kilobases of DNA homologous to the viral onc sequence interspersed with three intervening sequences.

摘要

急性转化型猫肉瘤病毒（斯奈德-泰伦毒株）的癌基因（v-fes）在包括人类在内的所有脊椎动物物种中都有同源细胞序列（c-fes）。我们从人类DNA文库中分离出了含有重叠c-fes序列的重组噬菌体。人类c-fes基因座跨度为3.4千碱基，包含1.4千碱基与病毒癌基因序列同源的DNA，其间穿插着三个间隔序列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/369889/e65010fa8719/molcellb00120-0143-a.jpg

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