类风湿关节炎中的血清铜及相关变量
Serum copper and related variables in rheumatoid arthritis.
作者信息
Scudder P R, Al-Timimi D, McMurray W, White A G, Zoob B C, Dormandy T L
出版信息
Ann Rheum Dis. 1978 Feb;37(1):67-70. doi: 10.1136/ard.37.1.67.
Abstract
Serum copper, caeruloplasmin, iron, iron-binding capacity, and antioxidant activity were measured in 120 normal subjects and in 189 patients with rheumatoid arthritis. Both serum copper and serum caeruloplasmin were significantly raised in rheumatoid disease in both sexes. A significant inverse relation was found between serum iron and serum copper, and a strong direct correlation between serum antioxidant activity and caeruloplasmin.
摘要
对120名正常受试者和189名类风湿性关节炎患者进行了血清铜、铜蓝蛋白、铁、铁结合能力和抗氧化活性的检测。在类风湿疾病中，男性和女性的血清铜和血清铜蓝蛋白均显著升高。血清铁与血清铜之间存在显著的负相关，血清抗氧化活性与铜蓝蛋白之间存在强烈的正相关。
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