Edelhauser H F, Gonnering R, Van Horn D L
Arch Ophthalmol. 1978 Mar;96(3):516-20. doi: 10.1001/archopht.1978.03910050284021.
Isolated human corneas maintained normal corneal thickness and endothelial ultrastructural integrity throughout a three-to four-hour period of perfusion of BSS plus to the endothelial surface. By comparison, only one of six human corneas perfused with lactated Ringer's solution was able to maintain normal thickness and ultrastructural integrity. The other five corneas perfused with lactated Ringer's solution showed various degrees of endothelial cell breakdown and corneal swelling during three hours of perfusion. The results of these studies suggest that BSS plus is a better solution for maintenance of human corneal endothelium during long-term (one- to three-hour) surgical procedures.
在长达三到四个小时的时间里，将平衡盐溶液加灌注到人类离体角膜的内皮表面，角膜能维持正常的角膜厚度和内皮超微结构完整性。相比之下，在灌注乳酸林格氏液的六个人类角膜中，只有一个能够维持正常厚度和超微结构完整性。另外五个灌注乳酸林格氏液的角膜在三小时的灌注过程中出现了不同程度的内皮细胞破坏和角膜肿胀。这些研究结果表明，在长期（一到三小时）的外科手术过程中，平衡盐溶液加是维持人类角膜内皮的更好溶液。
