Laulund S, Elling F, Saemundsen A K
Acta Pathol Microbiol Immunol Scand A. 1983 Jan;91(1):77-80. doi: 10.1111/j.1699-0463.1983.tb02729.x.
A 50-year-old Danish male presenting with swelling in fossa supraclavicularis and slight swelling of axillary and inguinal lymphnodes was diagnosed histologically as having malignant, non-Hodgkin, blast lymphoma. The EBV association was established by demonstration of EBV-DNA-positive tumor cells and the presence of high titers of antibodies of the IgG class to VCA, EA (D) and EBNA. The unique finding in this case was the high titers of IgA antibodies to VCA and to EA (D). This latter serological picture is characteristic of nasopharyngeal carcinoma (NPC) but has not previously been observed in Burkitt's lymphoma.
一名50岁的丹麦男性，表现为锁骨上窝肿胀以及腋窝和腹股沟淋巴结轻度肿大，经组织学诊断为恶性非霍奇金母细胞淋巴瘤。通过证明EBV-DNA阳性肿瘤细胞以及存在高滴度的IgG类抗VCA、EA（D）和EBNA抗体，确定了EBV关联。该病例的独特发现是抗VCA和抗EA（D）的IgA抗体滴度很高。后一种血清学表现是鼻咽癌（NPC）的特征，但以前在伯基特淋巴瘤中未观察到。
