抗轮状病毒中和单克隆抗体的衍生
Derivation of neutralizing monoclonal antibodies against rotavirus.
作者信息
Sonza S, Breschkin A M, Holmes I H
出版信息
J Virol. 1983 Mar;45(3):1143-6. doi: 10.1128/JVI.45.3.1143-1146.1983.
Abstract
Monoclonal antibodies were derived against the SA11 simian, NIC bovine, and Wa human rotavirus strains and characterized by enzyme-linked immunosorbent assay, plaque neutralization, and hemagglutination inhibition. Several strain SA11-specific antibodies were found to have neutralizing and hemagglutination-inhibiting capacity.
摘要
针对SA11猿猴轮状病毒株、NIC牛轮状病毒株和Wa人轮状病毒株制备了单克隆抗体，并通过酶联免疫吸附测定、蚀斑中和试验和血凝抑制试验对其进行了鉴定。发现几种SA11株特异性抗体具有中和及血凝抑制能力。
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