巨细胞病毒对B细胞的激活作用。
B cell activation by cytomegalovirus.
作者信息
Hutt-Fletcher L M, Balachandran N, Elkins M H
出版信息
J Exp Med. 1983 Dec 1;158(6):2171-6. doi: 10.1084/jem.158.6.2171.
Abstract
Human cytomegalovirus is shown to be a nonspecific polyclonal B cell activator. The B cell response is independent of virus replication and requires little, if any, T cell help.
摘要
人巨细胞病毒被证明是一种非特异性多克隆B细胞激活剂。B细胞反应独立于病毒复制，并且几乎不需要（如果需要的话）T细胞辅助。
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2
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