Skern T, Sommergruber W, Blaas D, Pieler C, Kuechler E
Virology. 1984 Jul 15;136(1):125-32. doi: 10.1016/0042-6822(84)90253-8.
cDNA clones representing the 3'-terminal region of the human rhinovirus strain 2 genome have been obtained. The sequence of 1425 nucleotides adjacent to the poly(A) tract is presented and contains an open reading frame of 1383 nucleotides. The derived amino acid sequence corresponding to the putative RNA polymerase-coding region is compared to those of poliovirus type 1 (Mahoney) and foot-and-mouth disease virus A12. A high degree of homology between human rhinovirus strain 2 and poliovirus type 1 (Mahoney) was found within the coding sequence but not within the 3'-untranslated region.
已获得代表人类鼻病毒2型基因组3'末端区域的cDNA克隆。给出了与聚腺苷酸序列相邻的1425个核苷酸的序列，其中包含一个1383个核苷酸的开放阅读框。将对应于推定的RNA聚合酶编码区的推导氨基酸序列与脊髓灰质炎病毒1型（马奥尼株）和口蹄疫病毒A12的氨基酸序列进行了比较。发现人类鼻病毒2型与脊髓灰质炎病毒1型（马奥尼株）在编码序列内具有高度同源性，但在3'非翻译区内则没有。
