1970年至1981年间在英国分离出的沙门氏菌中质粒编码的甲氧苄啶耐药性
Plasmid-encoded trimethoprim resistance in salmonellas isolated in Britain between 1970 and 1981.
作者信息
Threlfall E J, Frost J A, King H C, Rowe B
出版信息
J Hyg (Lond). 1983 Feb;90(1):55-60. doi: 10.1017/s002217240006383x.
Abstract
Trimethoprim resistance was plasmid-encoded in all trimethoprim-resistant Salmonella typhimurium and in the majority of trimethoprim-resistant salmonellas of other serotypes isolated since 1970 from humans and food animals in Britain. In S. typhimurium, non-autotransferring plasmids of compatibility group 3 and autotransferring plasmids of group H2 predominated. The predominance of these plasmid types has resulted from the spread of clones of trimethoprim-resistant strains of phage types 18, 170 and 204c. In other salmonellas, a variety of plasmid compatibility groups have been identified. Almost all plasmids which conferred resistance to trimethoprim also coded for sulphonamide resistance.
摘要
在英国，自1970年以来从人类和食用动物中分离出的所有耐甲氧苄啶鼠伤寒沙门氏菌以及大多数其他血清型的耐甲氧苄啶沙门氏菌中，甲氧苄啶耐药性是由质粒编码的。在鼠伤寒沙门氏菌中，相容性群3的非自传递质粒和H2群的自传递质粒占主导地位。这些质粒类型的优势源于噬菌体类型18、170和204c的耐甲氧苄啶菌株克隆的传播。在其他沙门氏菌中，已鉴定出多种质粒相容性群。几乎所有赋予对甲氧苄啶耐药性的质粒也编码对磺胺类药物的耐药性。
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