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对从西澳大利亚州无腹泻人群中分离出的产肠毒素大肠杆菌的研究。

Studies on enterotoxigenic Escherichia coli isolated from persons without diarrhoea in Western Australia.

作者信息

Berry R J, Bettelheim K A, Gracey M

出版信息

J Hyg (Lond). 1983 Feb;90(1):99-106. doi: 10.1017/s0022172400063890.

Abstract

The epidemiology of enterotoxigenic Escherichia coli (ETEC) was studied in children without diarrhoea in two remote Aboriginal communities in tropical north-western Australia. Serial surveys of the same individuals during different seasons showed that isolations were much more frequent in the wet monsoonal summer than in the dry winter. All E. coli were isolated from symptomless children aged 5 years or less; in addition, clearance of ETEC carriage without treatment was observed in all individuals within 3 months of isolation. Of the 58 ETEC strains isolated, 40 had either an H32 or an O126 antigen. Five O antigens which have never been associated with ETEC (O2, O41, O71, O77 and O157) were found. A recently proposed system to detect ETEC, using groups of polyvalent antisera, would have detected only 3 out of these 58 ETEC strains.

摘要

在澳大利亚西北部热带地区的两个偏远原住民社区,对无腹泻儿童的产肠毒素大肠杆菌(ETEC)流行病学进行了研究。在不同季节对同一批个体进行的系列调查显示,在潮湿的季风夏季,ETEC的分离率远高于干燥的冬季。所有大肠杆菌均从5岁及以下无症状儿童中分离得到;此外,在分离后的3个月内,所有个体未经治疗的情况下ETEC携带状态均消失。在分离出的58株ETEC菌株中,40株具有H32或O126抗原。发现了5种从未与ETEC相关联的O抗原(O2、O41、O71、O77和O157)。一种最近提出的使用多价抗血清组检测ETEC的系统,在这58株ETEC菌株中只能检测出3株。

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