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星形诺卡菌对多种抗生素的敏感性,包括新型β-内酰胺类、甲氧苄啶-磺胺甲恶唑、阿米卡星和N-甲酰亚胺硫霉素。

Susceptibility of Nocardia asteroides to various antibiotics, including newer beta-lactams, trimethoprim-sulfamethoxazole, amikacin, and N-formimidoyl thienamycin.

作者信息

Gombert M E

出版信息

Antimicrob Agents Chemother. 1982 Jun;21(6):1011-2. doi: 10.1128/AAC.21.6.1011.

Abstract

The susceptibility of 26 isolates of Nocardia asteroides to several antibiotics was determined by the agar dilution technique. Many currently available beta-lactam antibiotics were ineffective. Cefotaxime, cefmenoxime, and N-formimidoyl thienamycin were active against these strains, with 80% minimal inhibitory concentrations of 4, 4, and 2 micrograms/ml, respectively. Amikacin was the most effective agent tested.

摘要

采用琼脂稀释法测定了26株星形诺卡菌对几种抗生素的敏感性。许多目前可用的β-内酰胺类抗生素无效。头孢噻肟、头孢甲肟和N-甲酰亚胺硫霉素对这些菌株有活性,最低抑菌浓度80%分别为4、4和2微克/毫升。阿米卡星是所测试的最有效的药物。

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