Andersson S, Fredin H, Lindberg H, Sanzén L, Westlin N
Acta Orthop Scand. 1983 Apr;54(2):322-5. doi: 10.3109/17453678308996578.
One hundred patients with sprained ankles were randomly allocated to treatment with Ibuprofen 800 mg X 3 daily and placebo and to treatment with two qualities of compression bandaging. Neither Ibuprofen nor high quality bandaging had a significant effect on the swelling, pain or tenderness.