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酵母耐热性不需要蛋白质合成。

Yeast thermotolerance does not require protein synthesis.

作者信息

Hall B G

出版信息

J Bacteriol. 1983 Dec;156(3):1363-5. doi: 10.1128/jb.156.3.1363-1365.1983.

DOI:10.1128/jb.156.3.1363-1365.1983
PMID:6358199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC217991/
Abstract

Heat shock at 37 degrees C induces synthesis of stress (heat shock) proteins in Saccharomyces cerevisiae and also induces thermotolerance. Amino acid analogs that are powerful inducers of stress protein synthesis failed to induce thermotolerance, suggesting that the stress proteins do not play a causal role in acquired thermotolerance at 37 degrees C. This suggestion was confirmed by the observation that protein synthesis was not required for the induction of thermotolerance at 37 degrees C.

摘要

37摄氏度的热休克诱导酿酒酵母中应激(热休克)蛋白的合成,同时也诱导耐热性。作为应激蛋白合成强力诱导剂的氨基酸类似物未能诱导耐热性,这表明应激蛋白在37摄氏度时获得的耐热性中不发挥因果作用。蛋白质合成对于37摄氏度时耐热性的诱导并非必需,这一观察结果证实了上述观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/406b/217991/368ea7217b37/jbacter00241-0394-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/406b/217991/368ea7217b37/jbacter00241-0394-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/406b/217991/368ea7217b37/jbacter00241-0394-a.jpg

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本文引用的文献

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Transition series metals and sulfhydryl reagents induce the synthesis of four proteins in eukaryotic cells.过渡系列金属和巯基试剂可诱导真核细胞中四种蛋白质的合成。
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Methionine-mediated lethality in yeast cells at elevated temperature.甲硫氨酸在高温下对酵母细胞的致死作用。
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Induction of acquired thermotolerance in Tetrahymena thermophila: effects of protein synthesis inhibitors.嗜热四膜虫中获得性耐热性的诱导:蛋白质合成抑制剂的作用
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中国仓鼠卵巢细胞中的诱导热耐受性与热休克蛋白合成
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Polyhydroxy compounds and thermotolerance: a proposed concatenation.多羟基化合物与耐热性:一种假定的关联
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