Saner G, Yüzbasiyan V, Cigdem S
Br J Ind Med. 1984 May;41(2):263-6. doi: 10.1136/oem.41.2.263.
Hair and urine samples were collected from 34 male tannery workers and from 12 normal adults. Eighteen of the workers dealt directly with chromium and the remaining 16 (controls) worked in the offices and kitchen of the same factory. All were found to be clinically healthy. Chromium was determined by flameless atomic absorption spectroscopy. When compared with normal adult values, urinary chromium concentration, Cr/Creatinine ratio, daily chromium excretion, and hair chromium, concentrations were significantly higher and urinary beta 2-microglobulin/Cre ratios significantly lower in both tannery workers and in controls. A significant negative correlation was found between urinary beta 2-microglobulin/Cre and Cr/Cre ratios of tannery workers and controls. A significant positive correlation was shown between hair chromium and urinary Cr/Cre values in all workers. No correlations between the duration of exposure to chromium and hair and urinary chromium values were found. Nevertheless, high values observed in workers with short exposures show that chromium is readily absorbed through the respiratory system.
采集了34名男性制革厂工人和12名正常成年人的头发和尿液样本。其中18名工人直接接触铬，其余16名（对照组）在同一家工厂的办公室和厨房工作。所有人临床检查均健康。采用无火焰原子吸收光谱法测定铬含量。与正常成年人的值相比，制革厂工人和对照组的尿铬浓度、铬/肌酐比值、每日铬排泄量以及头发铬浓度均显著更高，而尿β2-微球蛋白/肌酐比值显著更低。在制革厂工人和对照组中，尿β2-微球蛋白/肌酐与铬/肌酐比值之间存在显著的负相关。在所有工人中，头发铬含量与尿铬/肌酐值之间呈显著正相关。未发现铬暴露时长与头发和尿铬值之间存在相关性。然而，短时间暴露的工人中观察到的高值表明铬很容易通过呼吸系统被吸收。
