Verschoor M A, Bragt P C, Herber R F, Zielhuis R L, Zwennis W C
Coronel Laboratory for Occupational and Environmental Health, University of Amsterdam, The Netherlands.
Int Arch Occup Environ Health. 1988;60(1):67-70. doi: 10.1007/BF00409381.
The influence of occupational exposure to water-soluble chromium (VI) on renal function was examined. In male chrome-plating workers (n = 29), stainless steel welders (n = 45), boilermakers (n = 18) and a control group of workers (n = 71), the level of chromium in the urine (Cr-U), the chromium clearance, and sensitive renal function parameters were determined. The glomerular-function parameters of the chrome-plating workers (Cr-U 1 to 34 micrograms/g creat) and welders (Cr-U 1 to 62 micrograms/g creatine) appeared to differ from those of the boilermakers (Cr-U 0.3 to 1.5 micrograms/g creatine) and controls (Cr-U 0.1 to 2 micrograms/g creatine). The renal function parameters were not related to chromium concentration in the urine or to chromium clearance.
研究了职业性接触水溶性六价铬对肾功能的影响。对男性镀铬工人(n = 29)、不锈钢焊工(n = 45)、锅炉制造工(n = 18)以及一组对照工人(n = 71),测定了尿铬水平(Cr-U)、铬清除率和敏感的肾功能参数。镀铬工人(Cr-U为1至34微克/克肌酐)和焊工(Cr-U为1至62微克/克肌酸)的肾小球功能参数似乎与锅炉制造工(Cr-U为0.3至1.5微克/克肌酸)和对照组(Cr-U为0.1至2微克/克肌酸)不同。肾功能参数与尿铬浓度或铬清除率无关。