Yaku Y, Kanda T, Yoshihara T, Kaneko T, Nagao K
Virchows Arch A Pathol Anat Histopathol. 1983;401(1):89-97. doi: 10.1007/BF00644792.
Two cases of undifferentiated carcinoma of the parotid gland were studied by light and electron microscopy. Light microscopy showed nests of ovoid cells with scanty cytoplasm and pyknotic nuclei in two cases. One case was the small-cell type, and another one was the large-cell type histopathologically. Electron microscopy showed two distinct cell types in each tumor: Case 1 (small-cell type). - An epithelial-like cell, and an irregular-shaped cell containing bundles of filaments suggesting myoepithelial differentiation. Case 2 (large-cell type). - An epithelial-like cell, and a large cell containing secretory-like granules. These findings support a salivary duct epithelial origin for these tumors.
通过光学显微镜和电子显微镜对两例腮腺未分化癌进行了研究。光学显微镜显示两例均为卵圆形细胞巢，细胞质稀少，细胞核固缩。组织病理学上，一例为小细胞型，另一例为大细胞型。电子显微镜显示每个肿瘤中有两种不同的细胞类型：病例1（小细胞型）- 一种上皮样细胞，以及一种含有束状细丝提示肌上皮分化的不规则形细胞。病例2（大细胞型）- 一种上皮样细胞，以及一种含有分泌样颗粒的大细胞。这些发现支持这些肿瘤起源于涎腺导管上皮。
