Mak J W, Lim P K
Z Parasitenkd. 1983;69(5):677-80. doi: 10.1007/BF00926677.
The chemoprophylactic use of diethylcarbamazine citrate at total oral doses of 15--180 mg/kg body weight was tested against subperiodic Brugia malayi infection in the leaf monkey (Presbytis melalophos). A total dose of 45 mg/kg body weight given over 9 days killed all developing infective larvae. Similarly, a total dose of 35 mg/kg body weight given over 7 days killed all fourth stage larvae. The minimum effective dose that prevents infection would be 5 mg/kg body weight daily for 7 days every month.
采用枸橼酸乙胺嗪进行化学预防，以15-180mg/kg体重的口服总剂量，针对叶猴（黑冠叶猴）体内的亚周期型马来布鲁线虫感染进行了试验。9天内给予45mg/kg体重的总剂量可杀死所有发育中的感染性幼虫。同样，7天内给予35mg/kg体重的总剂量可杀死所有四期幼虫。预防感染的最小有效剂量为每月7天，每天5mg/kg体重。
