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两个不连锁的基因座相互作用，以控制人类对B族链球菌III型抗原的免疫反应。

Two unlinked genetic loci interact to control the human immune response to type III group B streptococcal antigen.

作者信息

Pandey J P, Baker C J, Kasper D L, Fudenberg H H

出版信息

J Immunogenet. 1984 Apr;11(2):159-63. doi: 10.1111/j.1744-313x.1984.tb01051.x.

DOI:10.1111/j.1744-313x.1984.tb01051.x
PMID:6427356
Abstract

Serum samples were collected from 30 healthy adult Caucasian volunteers before and after immunization with native type III polysaccharide of group B streptococcus. Serum antibody to this polysaccharide was measured and sera were typed for several Gm and Km(1) allotypes. A significant interactive effect of Gm(23) and Km(1) was found on immune responsiveness to native type III group B streptococcus polysaccharide antigen.

摘要

从30名健康的成年白种人志愿者身上采集血清样本，这些志愿者在接种B族链球菌天然III型多糖之前和之后均被采集样本。检测了针对该多糖的血清抗体，并对血清进行了几种Gm和Km(1)同种异型分型。发现Gm(23)和Km(1)对天然III型B族链球菌多糖抗原的免疫反应性存在显著的交互作用。

相似文献

1
Two unlinked genetic loci interact to control the human immune response to type III group B streptococcal antigen.两个不连锁的基因座相互作用，以控制人类对B族链球菌III型抗原的免疫反应。
J Immunogenet. 1984 Apr;11(2):159-63. doi: 10.1111/j.1744-313x.1984.tb01051.x.
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Immunodeterminant specificity of human immunity to type III group B streptococcus.人类对B族链球菌III型免疫的免疫决定簇特异性。
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Interactive effect of Gm and Km allotypes on cellular immune responses to streptococcal cell wall antigen.Gm和Km同种异型对链球菌细胞壁抗原细胞免疫反应的交互作用。
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Immunoglobulin allotypes and immune response to meningococcal polysaccharides A and C.免疫球蛋白同种异型与对A群和C群脑膜炎球菌多糖的免疫反应。
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[Use of group A-specific polysaccharide antigen conjugated with protein carrier for detection of specific anti-polysaccharide antibodies].使用与蛋白质载体偶联的A群特异性多糖抗原检测特异性抗多糖抗体
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