Suzuki A, Mori M, Sakagami Y, Isogai A, Fujino M, Kitada C, Craig R A, Clewell D B
Science. 1984 Nov 16;226(4676):849-50. doi: 10.1126/science.6436978.
The Streptococcus faecalis sex pheromone cPD1, which induces a mating response in cells harboring the conjugative plasmid pPD1, has been isolated and its structure determined. It was found to have a molecular weight of 912, and its amino acid sequence was H-Phe-Leu-Val-Met-Phe-Leu-Ser-Gly-OH. A synthetic octapeptide showed the same biological activity and chromatographic behavior as the isolated cPD1. Pheromone activity was detectable at a concentration of approximately 4 X 10(-11)M.
粪肠球菌性信息素cPD1可在携带接合质粒pPD1的细胞中诱导交配反应，现已分离出该信息素并确定了其结构。发现它的分子量为912，其氨基酸序列为H-Phe-Leu-Val-Met-Phe-Leu-Ser-Gly-OH。一种合成八肽显示出与分离出的cPD1相同的生物活性和色谱行为。在浓度约为4×10(-11)M时可检测到信息素活性。
