粪肠球菌性信息素抑制剂iAM373的分离与结构
Isolation and structure of the sex pheromone inhibitor, iAM373, of Enterococcus faecalis.
作者信息
Nakayama J, Ono Y, Suzuki A
机构信息
Department of Applied Biological Chemistry, University of Tokyo, Japan.
出版信息
Biosci Biotechnol Biochem. 1995 Jul;59(7):1358-9. doi: 10.1271/bbb.59.1358.
PMID:7670199
Abstract
An Enterococcus faecalis plasmid, pAM373, has a high frequency of transfer in a liquid medium when induced by a recipient-produced sex pheromone, cAM373. The sex pheromone inhibitor against cAM373, termed iAM373, was isolated from a culture supernatant of E. faecalis harboring pAM377 (= pAM373::Tn917), and its structure was identified as a heptapeptide, H-Ser-Ile-Phe-Thr-Leu-Val-Ala-OH).
摘要
粪肠球菌质粒pAM373在由受体产生的性信息素cAM373诱导时，在液体培养基中有较高的转移频率。从携带pAM377（=pAM373::Tn917）的粪肠球菌培养上清液中分离出针对cAM373的性信息素抑制剂，称为iAM373，其结构被鉴定为一种七肽，H-丝氨酸-异亮氨酸-苯丙氨酸-苏氨酸-亮氨酸-缬氨酸-丙氨酸-OH）。
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