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青春期汗腺活动的诱导。

Pubertal induction of sweat gland activity.

作者信息

Rees J, Shuster S

出版信息

Clin Sci (Lond). 1981 Jun;60(6):689-92. doi: 10.1042/cs0600689.

DOI:10.1042/cs0600689
PMID:6454525
Abstract
  1. To study the difference in sweat rate between men and women the rates of cholinergic-induced sweating were measured in normal people before and after puberty and in response to androgens and anti-androgens. 2. Sweat rate in men was more than double that in women. 3. This difference did not occur in prepubertal boys and girls in whom the rate, corrected for surface area, was comparable with that in women. 4. Application or injection of androgen locally did not stimulate sweat production in the adult female. 5. Anti-androgen topically or systemically did not decrease sweat rate in men. 6. It is concluded that the rate of sweat rate in men is caused by androgen-induced gene expression at puberty and not by androgen modulation in adult life.
摘要
  1. 为研究男性和女性出汗率的差异,对正常人群在青春期前后以及使用雄激素和抗雄激素时胆碱能诱导出汗的速率进行了测量。2. 男性的出汗率是女性的两倍多。3. 这种差异在青春期前的男孩和女孩中并未出现,经体表面积校正后,他们的出汗率与女性相当。4. 局部应用或注射雄激素不会刺激成年女性出汗。5. 局部或全身使用抗雄激素不会降低男性的出汗率。6. 得出的结论是,男性出汗率是由青春期雄激素诱导的基因表达引起的,而非成年期雄激素的调节作用。

相似文献

1
Pubertal induction of sweat gland activity.青春期汗腺活动的诱导。
Clin Sci (Lond). 1981 Jun;60(6):689-92. doi: 10.1042/cs0600689.
2
A double-blind controlled cross-over trial of cyproterone acetate in females with hidradenitis suppurativa.醋酸环丙孕酮治疗化脓性汗腺炎女性患者的双盲对照交叉试验。
Br J Dermatol. 1986 Sep;115(3):263-8. doi: 10.1111/j.1365-2133.1986.tb05740.x.
3
Control of hidradenitis suppurativa in women using combined antiandrogen (cyproterone acetate) and oestrogen therapy.采用抗雄激素(醋酸环丙孕酮)和雌激素联合疗法治疗女性化脓性汗腺炎
Br J Dermatol. 1986 Sep;115(3):269-74. doi: 10.1111/j.1365-2133.1986.tb05741.x.
4
[Anti-androgen treatment of acne (author's transl)].痤疮的抗雄激素治疗(作者译)
Wien Klin Wochenschr. 1977 Sep 30;89(18):622-7.
5
Indirect evidence that the action of cyproterone acetate on the skin is due to a metabolite.
Clin Endocrinol (Oxf). 1983 Jul;19(1):53-5. doi: 10.1111/j.1365-2265.1983.tb00742.x.
6
Steroid inhibitors of androgen-potentiated actions on skin.雄激素对皮肤增强作用的类固醇抑制剂。
J Steroid Biochem. 1983 Jul;19(1B):587-90. doi: 10.1016/0022-4731(83)90222-4.
7
[Hormonal aspects of acne].[痤疮的激素方面]
Ann Dermatol Venereol. 1987;114(3):439-54.
8
Anti-androgens in treatment of acne vulgaris.抗雄激素药物治疗寻常痤疮
Int J Dermatol. 1985 Oct;24(8):533-4. doi: 10.1111/j.1365-4362.1985.tb05840.x.
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Pubertal development in girls with sexual precocity after discontinuation of treatment with cyproterone acetate.醋酸环丙孕酮治疗停止后性早熟女孩的青春期发育
Helv Paediatr Acta. 1980 May;35(2):149-54.
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Serum androgens in normal prepubertal and pubertal children and in children with precocious adrenarche.正常青春期前和青春期儿童以及性早熟儿童的血清雄激素
J Clin Endocrinol Metab. 1976 Jan;42(1):117-24. doi: 10.1210/jcem-42-1-117.

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