Noguchi T, Uzu A, Daigo K, Shida Y, Hashimoto K
Toxicon. 1984;22(3):425-32. doi: 10.1016/0041-0101(84)90086-2.
Toxins were extracted from the xanthid crab Atergatis floridus inhabiting Ishigaki Island, Okinawa, and subjected to several types of chromatography, resulting in separation into gonyautoxin and saxitoxin fractions. Thin-layer chromatographic and electrophoretic analyses showed that the gonyautoxin fraction was composed of gonyautoxins 1-4, along with some unknown compounds. Gas chromatography-mass spectrometry demonstrated that the gonyautoxin fraction gave rise to the C9-base when alkali-hydrolyzed, indicating that this fraction contained a tetrodotoxin-like compound possessing the quinazoline skeleton specific to tetrodotoxin. The saxitoxin fraction consisted of neosaxitoxin, saxitoxin and two unknown compounds.
从栖息于冲绳石垣岛的扇蟹中提取毒素，并对其进行了几种类型的色谱分析，结果分离出了膝沟藻毒素和石房蛤毒素组分。薄层色谱和电泳分析表明，膝沟藻毒素组分由膝沟藻毒素1 - 4以及一些未知化合物组成。气相色谱 - 质谱分析表明，膝沟藻毒素组分在碱水解时会产生C9碱基，这表明该组分含有一种具有河豚毒素特有的喹唑啉骨架的河豚毒素样化合物。石房蛤毒素组分由新石房蛤毒素、石房蛤毒素和两种未知化合物组成。
