de Natale R, Glaab-Schrems E, Krieglstein G K
Doc Ophthalmol. 1984 Dec 15;58(4):385-92. doi: 10.1007/BF00679801.
The efficacy of glaucoma therapy in preventing progression of glaucomatous field loss was investigated in a retrospective study. Hundred eyes with glaucomatous field defects of 71 patients were enrolled in the study. The mean observation period was 3.8 years. The evaluation of potential visual field changes was made with the biostatistical program Delta of the Octopus computerized perimeter. All field examinations were done with the same automated perimeter (Octopus, model 201). In 19% of the eyes adequate medical or surgical therapy failed to arrest the disease process. Improvement or deterioration of the whole field can be simulated by changes of the pupillary diameter, whereas deterioration in the pathologic area only is highly specific for progression of the glaucomatous process.
在一项回顾性研究中,对青光眼治疗预防青光眼性视野缺损进展的疗效进行了调查。该研究纳入了71例患者的100只患有青光眼性视野缺损的眼睛。平均观察期为3.8年。使用章鱼电脑视野计的生物统计学程序Delta对潜在的视野变化进行评估。所有视野检查均使用同一台自动视野计(章鱼201型)进行。在19%的眼睛中,适当的药物或手术治疗未能阻止疾病进程。整个视野的改善或恶化可通过瞳孔直径的变化来模拟,而仅病理性区域的恶化对青光眼进程的进展具有高度特异性。