Dahl J E
Acta Odontol Scand. 1984 Aug;42(4):251-5. doi: 10.3109/00016358408993878.
Methylmercury chloride, a well-known nerve cell toxicant, was administered to 40 rats in 2 groups, in doses of 10 mg/kg and 20 mg/kg. Histomorphologic investigation of maxillary incisors after 2 and 4 days revealed granular and hydropic changes in parts of the odontoblastema. Deposition of interglobular dentin was seen after 7 and 11 days. The most vulnerable cells seemed to be the mantle dentin-producing odontoblasts, and the alterations found are probably due to interference with the rough endoplasmic reticulum.
氯化甲基汞是一种著名的神经细胞毒物，将其以10毫克/千克和20毫克/千克的剂量分别给予两组共40只大鼠。在2天和4天后对上颌切牙进行组织形态学研究，发现成牙本质细胞层部分出现颗粒状和水样变性。在7天和11天后可见球间牙本质沉积。最易受影响的细胞似乎是产生罩牙本质的成牙本质细胞，所发现的改变可能是由于对粗面内质网的干扰所致。
