人淋巴细胞表面IgG亚类：单克隆抗体研究
Subclasses of IgG on the surface of human lymphocytes: a study with monoclonal antibodies.
作者信息
Partridge L, Jefferis R, Hardie D, Ling N R, Richardson P
出版信息
Clin Exp Immunol. 1984 Apr;56(1):167-74.
Abstract
Cells from sIgG+ B lymphoblastoid cell lines, sIgG+ B cell neoplasms and from tonsils, adult and cord blood and fetal spleen were tested for IgG subclass expression using a panel of monoclonal antibodies. IgG1 was in all cases the commonest subclass except on blood lymphocytes, when approximately equal numbers of cells expressing IgG1 and IgG2 were found. No evidence for multiple subclass isotype expression was found.
摘要
使用一组单克隆抗体，对来自分泌免疫球蛋白G（sIgG）阳性B淋巴母细胞系、sIgG阳性B细胞肿瘤以及扁桃体、成人血液、脐带血和胎儿脾脏的细胞进行了IgG亚类表达检测。除了血液淋巴细胞外，在所有情况下IgG1都是最常见的亚类，在血液淋巴细胞中，发现表达IgG1和IgG2的细胞数量大致相等。未发现多重亚类同种型表达的证据。
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