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人淋巴细胞表面IgG亚类：单克隆抗体研究

Subclasses of IgG on the surface of human lymphocytes: a study with monoclonal antibodies.

作者信息

Partridge L, Jefferis R, Hardie D, Ling N R, Richardson P

出版信息

Clin Exp Immunol. 1984 Apr;56(1):167-74.

PMID:6609031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1535947/
Abstract

Cells from sIgG+ B lymphoblastoid cell lines, sIgG+ B cell neoplasms and from tonsils, adult and cord blood and fetal spleen were tested for IgG subclass expression using a panel of monoclonal antibodies. IgG1 was in all cases the commonest subclass except on blood lymphocytes, when approximately equal numbers of cells expressing IgG1 and IgG2 were found. No evidence for multiple subclass isotype expression was found.

摘要

使用一组单克隆抗体，对来自分泌免疫球蛋白G（sIgG）阳性B淋巴母细胞系、sIgG阳性B细胞肿瘤以及扁桃体、成人血液、脐带血和胎儿脾脏的细胞进行了IgG亚类表达检测。除了血液淋巴细胞外，在所有情况下IgG1都是最常见的亚类，在血液淋巴细胞中，发现表达IgG1和IgG2的细胞数量大致相等。未发现多重亚类同种型表达的证据。

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Subclasses of IgG on the surface of human lymphocytes: a study with monoclonal antibodies.人淋巴细胞表面IgG亚类：单克隆抗体研究
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引用本文的文献

1
Surface IgG subclasses in human B cell lymphomas as revealed by monoclonal antibodies.单克隆抗体揭示的人类B细胞淋巴瘤中的表面IgG亚类
Clin Exp Immunol. 1984 Jul;57(1):163-70.
2
Selective IgG subclass deficiency: quantification and clinical relevance.选择性IgG亚类缺陷：定量分析及其临床意义
Clin Exp Immunol. 1990 Sep;81(3):357-67. doi: 10.1111/j.1365-2249.1990.tb05339.x.

本文引用的文献

1
H CHAIN SUBGROUPS OF MYELOMA PROTEINS AND NORMAL 7S GAMMA-GLOBULIN.骨髓瘤蛋白和正常7Sγ球蛋白的重链亚群
J Exp Med. 1964 Aug 1;120(2):253-66. doi: 10.1084/jem.120.2.253.
2
SUBCLASSES OF HUMAN GAMMA-2-GLOBULIN BASED ON DIFFERENCES IN THE HEAVY POLYPEPTIDE CHAINS.基于重多肽链差异的人γ-2球蛋白亚类
Science. 1964 Oct 16;146(3642):400-1. doi: 10.1126/science.146.3642.400.
3
A critical appraisal of the direct antibody-rosette test for the detection of cell surface antigens.对用于检测细胞表面抗原的直接抗体玫瑰花结试验的批判性评价。
J Immunol Methods. 1981;47(3):265-74. doi: 10.1016/0022-1759(81)90282-9.
4
Distribution of surface, cytoplasmic and secreted IgG subclasses in human lymphoblastoid cell lines and normal peripheral blood lymphocytes.人淋巴母细胞系和正常外周血淋巴细胞中表面、细胞质和分泌型IgG亚类的分布
Scand J Immunol. 1981 Jul;14(1):1-13. doi: 10.1111/j.1365-3083.1981.tb00178.x.
5
Distribution of IgG subclasses in human B lymphocytes: evidence for dual expression of subclasses in surface and cytoplasmic IgG in minor B lymphocyte subpopulations.人B淋巴细胞中IgG亚类的分布：小部分B淋巴细胞亚群中表面和细胞质IgG亚类双重表达的证据。
J Immunol. 1980 Jan;124(1):431-6.
6
Multiple heavy chain isotypes on the membrane of the small B lymphocytes in human blood.人类血液中小B淋巴细胞细胞膜上的多种重链同种型。
Clin Exp Immunol. 1981 Jan;43(1):149-56.
7
Properties of monoclonal antibodies to human immunoglobulin kappa and lambda chains.抗人免疫球蛋白κ和λ链单克隆抗体的特性
Immunology. 1981 Apr;42(4):649-59.
8
The IgG subclass responses of human lymphocytes to B-cell activators.人类淋巴细胞对B细胞激活剂的IgG亚类反应。
Immunology. 1983 Oct;50(2):269-72.
9
IgG subclass expression by human B lymphocytes and plasma cells: B lymphocytes precommitted to IgG subclass can be preferentially induced by polyclonal mitogens with T cell help.人B淋巴细胞和浆细胞的IgG亚类表达：预先倾向于特定IgG亚类的B淋巴细胞可在T细胞辅助下，由多克隆有丝分裂原优先诱导产生。
J Immunol. 1983 Feb;130(2):671-7.
10
Monoclonal antibodies (McAbs) to determinants on human gamma chains: properties of antibodies showing subclass restriction or subclass specificity.针对人γ链上决定簇的单克隆抗体（McAbs）：表现出亚类限制或亚类特异性的抗体特性。
Immunology. 1982 Oct;47(2):329-36.