Matsuda M, Sugishita Y, Koseki S, Ito I, Akatsuka T, Takamatsu K
J Appl Physiol Respir Environ Exerc Physiol. 1983 Aug;55(2):323-8. doi: 10.1152/jappl.1983.55.2.323.
To evaluate the effect of exercise on left ventricular diastolic filling, the following were measured at rest and during exercise in 14 control subjects and 15 athletes, using digitized M-mode echocardiography: the peak early diastolic lengthening rate of the left ventricular dimension and the filling volume and the filling fraction during the first 0.10 s of diastole. During ergometer exercise performed at a level that increased the heart rate to 100 beats/min, there were significant increases in the peak normalized lengthening rate of the left ventricular dimension (control subjects, 4.2 +/- 1.3 vs. 6.1 +/- 1.1 s-1, mean +/- SD, P less than 0.001; athletes, 5.3 +/- 0.9 vs. 7.4 +/- 1.1 s-1, P less than 0.001), filling volume (control subjects, 15 +/- 12 vs. 33 +/- 10 ml, P less than 0.001; athletes, 21 +/- 12 vs. 63 +/- 18 ml, P less than 0.001), and filling fraction (control subjects, 21 +/- 14 vs. 42 +/- 17%, P less than 0.005; athletes, 21 +/- 13 vs. 54 +/- 12%, P less than 0.01). The peak lengthening rate of the left ventricular dimension, the filling volume, and the filling fraction were significantly greater in athletes than in control subjects during exercise (P less than 0.005, P less than 0.001, and P less than 0.05, respectively). Augmented early diastolic filling may be a mechanism to provide adequate filling for the ventricle at high heart rates produced by exercise, especially in athletes.
为评估运动对左心室舒张期充盈的影响，采用数字化M型超声心动图，在14名对照受试者和15名运动员静息状态及运动过程中测量了以下指标：左心室直径舒张早期峰值延长率、舒张期最初0.10秒内的充盈量和充盈分数。在进行使心率增加至100次/分钟水平的测力计运动期间，左心室直径峰值标准化延长率（对照受试者，4.2±1.3对6.1±1.1 s-1，平均值±标准差，P<0.001；运动员，5.3±0.9对7.4±1.1 s-1，P<0.001）、充盈量（对照受试者，15±12对33±10 ml，P<0.001；运动员，21±12对63±18 ml，P<0.001）和充盈分数（对照受试者，21±14对42±17%，P<0.005；运动员，21±13对54±12%，P<0.01）均显著增加。运动期间，运动员的左心室直径峰值延长率、充盈量和充盈分数显著高于对照受试者（分别为P<0.005、P<0.001和P<0.05）。舒张早期充盈增加可能是一种机制，可为运动产生的高心率时的心室提供足够的充盈，尤其是在运动员中。
