新型β-内酰胺类抗生素对不动杆菌属的体外活性
In vitro activities of new beta-lactam antibiotics against Acinetobacter spp.
作者信息
Garcia I, Fainstein V, LeBlanc B, Bodey G P
出版信息
Antimicrob Agents Chemother. 1983 Aug;24(2):297-9. doi: 10.1128/AAC.24.2.297.
Abstract
The in vitro activities of new beta-lactam antibiotics was studied and compared with those of other known agents against 51 clinical isolates of Acinetobacter calcoaceticus subsp. anitratus and 23 isolates of A. calcoaceticus subsp. lwoffi. Of the new beta-lactam antibiotics, imipemide (N-formimidoyl thienamycin), ceftazidime, ceftizoxime, ceftriaxone, and piperacillin demonstrated good activities. The minimal inhibitory concentrations for A. calcoaceticus subsp. lwoffi were lower than those obtained for A. calcoaceticus subsp. anitratus.
摘要
研究了新型β-内酰胺类抗生素对51株醋酸钙不动杆菌反硝化亚种和23株醋酸钙不动杆菌鲁氏亚种临床分离株的体外活性，并与其他已知药物进行了比较。在新型β-内酰胺类抗生素中，亚胺培南（N-甲酰亚胺基硫霉素）、头孢他啶、头孢唑肟、头孢曲松和哌拉西林表现出良好的活性。醋酸钙不动杆菌鲁氏亚种的最低抑菌浓度低于醋酸钙不动杆菌反硝化亚种。
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