Atkin A, Bodis-Wollner I, Podos S M, Wolkstein M, Mylin L, Nitzberg S
Invest Ophthalmol Vis Sci. 1983 Nov;24(11):1524-8.
Latency of the pattern visual-evoked potential (PVEP) was measured in 24 ocular hypertensive (OHT) patients, eight open-angle glaucoma (OAG) patients, and 37 control subjects. The PVEP stimulus was a 2.3 cycle/degree sinusoidal grating, counterphase-modulated at 1 Hz. Field size was 9 degrees and mean luminance 1.7 log ft-lamberts. For 22 of the 32 patients, a psycholphysical measure of dynamic contrast sensitivity at 8 Hz (DRC) was obtained with a 4 degrees diameter stimulus, by determining the mean value for the contrast sensitivities to a homogeneous flickering field and to a 1.2 cycle/degree counterphase-flickering grating. Patient DRC values were compared with previously published control data from 21 subjects. Mean PVEP latencies of both the OHT and the OAG patients were greater than normal (P less than 0.001), with the OAG value larger than the OHT value (P less than 0.001). Mean DRCs were lower than normal (P less than 0.002) for both patient groups, with the OAG value lower than the OHT value (P less than 0.025). DRC correlated with PVEP latency for these patients (r = -0.66, P less than 0.001).
对24例高眼压症（OHT）患者、8例开角型青光眼（OAG）患者和37名对照者测量了图形视觉诱发电位（PVEP）的潜伏期。PVEP刺激为2.3周/度的正弦光栅，以1Hz进行反相调制。视野大小为9度，平均亮度为1.7对数英尺朗伯。对于32例患者中的22例，通过确定对均匀闪烁视野和1.2周/度反相闪烁光栅的对比敏感度的平均值，使用直径为4度的刺激获得了8Hz时动态对比敏感度（DRC）的心理物理学测量值。将患者的DRC值与之前发表的21名受试者的对照数据进行比较。OHT患者和OAG患者的平均PVEP潜伏期均高于正常水平（P<0.001），且OAG患者的值大于OHT患者的值（P<0.001）。两组患者的平均DRC均低于正常水平（P<0.002），且OAG患者的值低于OHT患者的值（P<0.025）。这些患者的DRC与PVEP潜伏期相关（r = -0.66，P<0.001）。
