人类异烟肼代谢的形式遗传学。
Formal genetics of isoniazid metabolism in man.
作者信息
Iselius L, Evans D A
出版信息
Clin Pharmacokinet. 1983 Nov-Dec;8(6):541-4. doi: 10.2165/00003088-198308060-00005.
Abstract
Complex segregation analysis of the isoniazid inactivator phenotype has shown the existence of a recessive gene and a multifactorial background. The phenotype is also influenced by age, sex and weight. The relevance of these findings to the grouping of individuals into slow and rapid inactivators is stressed.
摘要
对异烟肼灭活剂表型的复杂分离分析表明存在一个隐性基因和一个多因素背景。该表型还受年龄、性别和体重的影响。强调了这些发现与将个体分为慢灭活剂和快灭活剂组别的相关性。
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