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科茨病：临床、血管造影、组织病理学表现及临床处理

Coat's disease: clinical, angiographic, histopathological findings and clinical management.

作者信息

Tarkkanen A, Laatikainen L

出版信息

Br J Ophthalmol. 1983 Nov;67(11):766-76. doi: 10.1136/bjo.67.11.766.

DOI:10.1136/bjo.67.11.766
PMID:6685529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040196/
Abstract

Twenty-four consecutive patients with Coats's disease are reported. In 9 cases the blind eye was enucleated because of total exudative detachment of the retina or because of untreatable secondary glaucoma. No treatment had been given. Fifteen patients between 22 months and 52 years of age were managed by argon laser or xenon photocoagulation and/or cryocoagulation. The number of treatment sessions varied from 1 to 9 per patient and totalled 49 sessions. Fluorescein angiography was performed in all cases. In most eyes the arterial system seemed to be more damaged than the venous side. Many arterioles ended in macroaneurysm-like dilatations surrounded by avascular areas or complete vascular closure in more advanced cases. In 11 out of 14 eyes the vision improved after treatment or remained unchanged. The follow-up varied from 1 to 8 years. Persistent and aggressive long-term treatment of Coats's disease is recommended because the prognosis without treatment is poor.

摘要

报告了24例连续性Coats病患者。9例患者因视网膜完全渗出性脱离或因无法治疗的继发性青光眼而摘除了盲眼。这些患者此前未接受过任何治疗。15例年龄在22个月至52岁之间的患者接受了氩激光或氙光凝和/或冷冻治疗。每位患者的治疗次数从1次到9次不等，总计49次治疗。所有病例均进行了荧光素血管造影。在大多数眼中，动脉系统似乎比静脉侧受损更严重。许多小动脉末端呈大动脉瘤样扩张，周围有无血管区，在更晚期病例中出现完全血管闭塞。14只眼中有11只眼在治疗后视力改善或保持不变。随访时间为1至8年。由于未经治疗的预后较差，建议对Coats病进行持续且积极的长期治疗。

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COATS'S DISEASE. I. REVIEW OF THE LITERATURE, DIAGNOSTIC CRITERIA, CLINICAL FINDINGS, AND PLASMA LIPID STUDIES.科茨病。一、文献综述、诊断标准、临床发现及血浆脂质研究
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COATS' DISEASE.
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Coats' disease: trends and long-term treatment outcomes in a tertiary referral centre.科茨病：三级转诊中心的趋势及长期治疗结果
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Clinical Characteristics of Pediatric Coats' Disease With Retinal Cyst Using Wide-Angle Fluorescein Angiography.使用广角荧光素血管造影术观察小儿科茨病合并视网膜囊肿的临床特征
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SUBCLINICAL MACULAR CHANGES AND DISEASE LATERALITY IN PEDIATRIC COATS DISEASE DETERMINED BY QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.定量光学相干断层扫描血管造影术在小儿 Coats 病中的亚临床黄斑改变和疾病侧别判断。
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Fluorescein Angiographic Abnormalities in the Contralateral Eye with Normal Fundus in Children with Unilateral Coats' Disease.单侧科茨病患儿对侧眼底正常眼中的荧光素血管造影异常
Korean J Ophthalmol. 2018 Feb;32(1):65-69. doi: 10.3341/kjo.2016.0092. Epub 2018 Jan 25.
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Coats' disease.
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Idiopathic juxtafoveolar retinal telangiectasis.
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