Bannwart C, Fotsis T, Heikkinen R, Adlercreutz H
Clin Chim Acta. 1984 Jan 31;136(2-3):165-72. doi: 10.1016/0009-8981(84)90288-2.
The identification by gas chromatography-mass spectrometry of the isoflavonic phytoestrogen daidzein [7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one] for the first time in human urine is described. The metabolism and effect on reproduction of isoflavones in animals and the possible significance of phytoestrogens in man is discussed. Preliminary results on the quantitative excretion of daidzein in female subjects consuming different diets are also reported.
本文描述了首次通过气相色谱 - 质谱法在人尿中鉴定出异黄酮类植物雌激素大豆苷元[7 - 羟基 - 3 - (4 - 羟基苯基)-4H - 1 - 苯并吡喃 - 4 - 酮]。讨论了异黄酮在动物体内的代谢及其对生殖的影响,以及植物雌激素在人体内可能具有的意义。还报道了食用不同饮食的女性受试者中大豆苷元定量排泄的初步结果。