Nelson K B, Ellenberg J H
JAMA. 1984 Apr 13;251(14):1843-8.
In a prospective study, late obstetric complications were common, one or more occurring in 62% of 51,285 pregnancies. We examined these complications as risk factors for cerebral palsy (CP) or nonfebrile seizure disorders. Certain complications were associated with an increased rate of CP, but in babies over 2,500 g, the observed rate of CP did not exceed 2% following any condition evaluated. For most conditions, the CP rate was highest in the small subgroup of children who had five-minute Apgar scores of 3 or less. Most babies over 2,500 g born after each complication achieved five-minute Apgar scores of 7 or higher, and for them the risk of CP was not significantly greater than in children whose births were uncomplicated. Neither the complications considered nor Apgar scores were important antecedents of nonfebrile seizure disorders in children free of CP.
在一项前瞻性研究中，晚期产科并发症很常见，在51285例妊娠中有62%出现了一种或多种并发症。我们将这些并发症作为脑瘫（CP）或非热性惊厥障碍的风险因素进行了研究。某些并发症与CP发生率增加有关，但在体重超过2500克的婴儿中，在评估的任何情况下，观察到的CP发生率均未超过2%。对于大多数情况，5分钟阿氏评分3分或更低的儿童小亚组中CP发生率最高。每种并发症后出生的大多数体重超过2500克的婴儿5分钟阿氏评分达到7分或更高，对他们来说，CP风险并不显著高于出生无并发症的儿童。在无CP的儿童中，所考虑的并发症和阿氏评分均不是非热性惊厥障碍的重要先兆。
