甲型流感病毒A/苏联/90/77神经氨酸酶基因的核苷酸序列。
Nucleotide sequence of the influenza virus A/USSR/90/77 neuraminidase gene.
作者信息
Concannon P, Kwolek C J, Salser W A
出版信息
J Virol. 1984 May;50(2):654-6. doi: 10.1128/JVI.50.2.654-656.1984.
Abstract
The complete nucleotide sequence of the N1 neuraminidase gene of influenza virus A/USSR/90/77 was determined. Comparison of its predicted amino acid sequence with other N1 and N2 neuraminidases indicates that the N1 neuraminidases share most of the antigenic determinants mapped on the N2 neuraminidase but display at least one additional potentially antigenic region probably as a result of intersubtypic differences in glycosylation.
摘要
测定了甲型流感病毒A/苏联/90/77的N1神经氨酸酶基因的完整核苷酸序列。将其预测的氨基酸序列与其他N1和N2神经氨酸酶进行比较表明，N1神经氨酸酶共享了定位在N2神经氨酸酶上的大多数抗原决定簇，但显示出至少一个额外的潜在抗原区域，这可能是糖基化亚型间差异的结果。
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