Sober A J, Wick M M
JAMA. 1978 Aug 11;240(6):554-5.
Concern has been voiced over a role for levodopa in the induction or stimulation of growth of cutaneous malignant melanoma. Prospective query of 1,099 patients of the Melanoma Clinical Cooperative Group at the time of presentation of their primary melanoma showed only one patient who had been taking levodopa. It was concluded that levodopa, if a factor in the induction of melanoma, must be playing an inconsequential role in the rapid rise in incidence observed for this tumor over the past decade.
左旋多巴在皮肤恶性黑色素瘤的诱发或生长刺激中所起的作用已引发关注。对黑色素瘤临床协作组的1099例原发性黑色素瘤患者初诊时进行前瞻性调查发现，仅有1例患者正在服用左旋多巴。得出的结论是，左旋多巴即便在黑色素瘤诱发过程中是一个因素，在过去十年中该肿瘤发病率的快速上升方面，其作用也必定微不足道。
