新生儿败血症中C反应蛋白的系列研究
Serial study of C reactive protein in neonatal septicaemia.
作者信息
Hindocha P, Campbell C A, Gould J D, Wojciechowski A, Wood C B
出版信息
Arch Dis Child. 1984 May;59(5):435-8. doi: 10.1136/adc.59.5.435.
Serial C reactive protein concentrations were assayed by electroimmunoassay in 41 infants. Values in most of the non-infected infants were below 0.3 mg/dl, the lower limit of detection of C reactive protein by electroimmunoassay. Eleven of 12 infants with proved sepsis (positive blood cultures) had significantly raised concentrations and one infant with recurrent pseudomonas chest infection had a raised C reactive protein concentration. High C reactive protein concentrations were also found in infants with suspected infection. Successful treatment was followed by a decrease in the C reactive protein concentration. Total white blood cell count was not as appropriate as C reactive protein determination in the early identification of bacterial infection in the newborn.
采用免疫电泳法对41例婴儿的C反应蛋白浓度进行了连续检测。大多数未感染婴儿的值低于0.3mg/dl，这是免疫电泳法检测C反应蛋白的下限。12例已证实败血症（血培养阳性）的婴儿中有11例C反应蛋白浓度显著升高，1例复发性假单胞菌胸部感染婴儿的C反应蛋白浓度也升高。疑似感染的婴儿中也发现了高C反应蛋白浓度。治疗成功后，C反应蛋白浓度下降。在新生儿细菌感染的早期识别中，总白细胞计数不如C反应蛋白测定合适。
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